Health-Related Quality of Life Among Children With Pneumonia in Indonesia Using the EuroQoL Descriptive System Value Set for Indonesia

Hadning, Ingenida; Andayani, Tri Murti; Endarti, Dwi; Triasih, Rina

doi:10.1016/j.vhri.2020.05.010

Cited by 2 publications

(3 citation statements)

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“…The median length of hospital stay was 4 days IQR [ 2 – 7 ] for children hospitalised with a severe pneumonia for the first time; and 5 days IQR [ 3 – 8 ] for children readmitted with severe pneumonia. We noted that children readmitted with severe pneumonia were hospitalised for longer than seven days more frequently than those admitted for the first time with severe pneumonia (34% vs. 26%, p < 0.001).…”

Section: Resultsmentioning

confidence: 99%

“…In many low-and-middle-income-countries (LMICs), children and adolescents disproportionately face the double burden of acute respiratory infectious diseases and chronic comorbidities, resulting in long-term impairment of lung function [ 1 , 2 ], reduced quality of life [ 3 ], and mortality [ 4 ]. Presence of chronic comorbidities and prior severe pneumonia episodes increase the risk of pneumonia re-admission and is associated with substantial costs [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

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Characteristics of children readmitted with severe pneumonia in Kenyan hospitals

Marangu-Boore,

Mwaniki,

Isaaka

et al. 2024

BMC Public Health

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Background Pneumonia is a leading cause of childhood morbidity and mortality. Hospital re-admission may signify missed opportunities for care or undiagnosed comorbidities. Methods We conducted a retrospective cohort study including children aged $$\ge$$ ≥ 2 months-14 years hospitalised with severe pneumonia between 2013 and 2021 in a network of 20 primary referral hospitals in Kenya. Severe pneumonia was defined using the 2013 World Health Organization criteria, and re-admission was based on clinical documentation from individual patient case notes. We estimated the prevalence of re-admission, described clinical management practices, and modelled risk factors for re-admission and inpatient mortality. Results Among 20,603 children diagnosed with severe pneumonia, 2,274 (11.0%, 95% CI 10.6–11.5) were readmitted. Re-admission was independently associated with age (12–59 months vs. 2–11 months: adjusted odds ratio (aOR) 1.70, 1.54–1.87; >5 years vs. 2–11 months: aOR 1.85, 1.55–2.22), malnutrition (weight-for-age-z-score (WAZ) <-3SD vs. WAZ> -2SD: aOR 2.05, 1.84–2.29); WAZ − 2 to -3 SD vs. WAZ> -2SD: aOR 1.37, 1.20–1.57), wheeze (aOR 1.17, 1.03–1.33) and presence of a concurrent neurological disorder (aOR 4.42, 1.70-11.48). Chest radiography was ordered more frequently among those readmitted (540/2,274 [23.7%] vs. 3,102/18,329 [16.9%], p < 0.001). Readmitted patients more frequently received second-line antibiotics (808/2,256 [35.8%] vs. 5,538/18,173 [30.5%], p < 0.001), TB medication (69/2,256 [3.1%] vs. 298/18,173 [1.6%], p < 0.001), salbutamol (530/2,256 [23.5%] vs. 3,707/18,173 [20.4%], p = 0.003), and prednisolone (157/2,256 [7.0%] vs. 764/18,173 [4.2%], p < 0.001). Inpatient mortality was 2,354/18,329 (12.8%) among children admitted with a first episode of severe pneumonia and 269/2,274 (11.8%) among those who were readmitted (adjusted hazard ratio (aHR) 0.93, 95% CI 0.82–1.07). Age (12–59 months vs. 2–11 months: aHR 0.62, 0.57–0.67), male sex (aHR 0.81, 0.75–0.88), malnutrition (WAZ <-3SD vs. WAZ >-2SD: aHR 1.87, 1.71–2.05); WAZ − 2 to -3 SD vs. WAZ >-2SD: aHR 1.46, 1.31–1.63), complete vaccination (aHR 0.74, 0.60–0.91), wheeze (aHR 0.87, 0.78–0.98) and anaemia (aHR 2.14, 1.89–2.43) were independently associated with mortality. Conclusions Children readmitted with severe pneumonia account for a substantial proportion of pneumonia hospitalisations and deaths. Further research is required to develop evidence-based approaches to screening, case management, and follow-up of children with severe pneumonia, prioritising those with underlying risk factors for readmission and mortality.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Characteristics of children readmitted with severe pneumonia in Kenyan hospitals

Marangu-Boore,

Mwaniki,

Isaaka

et al. 2024

BMC Public Health

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“…Studies in Indonesia and Thailand have also reported HUS of the patients using the proxy version of EQ-5D. 9 10 However, no studies have yet provided available data on HUS for the Chinese paediatric patients.…”

Section: Introductionmentioning

confidence: 99%

Health-related quality of life and economic burden of childhood pneumonia in China: a multiregion study

Gao,

Fan,

Zhou

et al. 2023

bmjpo

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ObjectiveTo systematically investigate the health-related quality of life (HRQOL) and economic burden of children with pneumonia in different regions of China.Study designThe study recruited a series of children under 5 years hospitalised for pneumonia in Shanghai, Zhengzhou and Kunming from January to October 2019.Health utility was assessed using the proxy version of EQ-5D-Y by interviewing patients’ guardians face to face. The assessment was administered twice at patients’ admission and discharge. Cost incurred for receiving the hospitalisation was collected. Multiple linear regression and quantile regression were used to explore factors of EQ-5D-Y Health Utility Score (HUS) and costs, respectively.ResultsA total of 501 paediatric patients with a median age (IQR) of 1.5 (0.83–2.71) years were included in the analysis. The mean HUS (SD) of the patients was 0.78 (0.18) at admission, and increased to 0.96 (0.10) at discharge. Some patients (14.2%) still felt worried, sad or unhappy after hospitalisation. The mean hospitalisation cost and total cost were RMB5859 (€773) and RMB6439, respectively. The HUS was lower and the economic burden was heavier for the children in Zhengzhou. Apart from region, type of work, insurance status and hospital days were also related to the baseline HUS or HUS increment after treatment; insurance status, Visual Analogue Scale score at discharge, guardians’ employment and hospitalisation days were associated with the costs.ConclusionThe children with pneumonia have poor baseline HRQOL, and many of them still have psychological well being problems after treatment. The economic burden varied significantly across regions and is heavy for the patients’ families in less developed areas (ie, Zhengzhou and Kunming).

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Health-Related Quality of Life Among Children With Pneumonia in Indonesia Using the EuroQoL Descriptive System Value Set for Indonesia

Cited by 2 publications

References 21 publications

Characteristics of children readmitted with severe pneumonia in Kenyan hospitals

Characteristics of children readmitted with severe pneumonia in Kenyan hospitals

Health-related quality of life and economic burden of childhood pneumonia in China: a multiregion study

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