“…Fishing is strongly demanding, both physically and psychologically, implying, among the several challenges, working long hours, frequent night shifts, the unpredictability of the sea, and prolonged separation from the family [184]. Moreover, several investigations have linked the above factors to health conditions and harmful habits that are common among fishermen from different parts of the world, including the Mediterranean Sea [185], which comprise tobacco smoking, alcohol abuse, sleep deprivation, chronic stress, and so on [186,187]. Such habits are known to impact human DNA methylation [188][189][190][191], and hence must be taken into consideration when asking sampled individuals about their daily life.…”