Health‐related behaviors and mental health states of South Korean adolescents with atopic dermatitis

Abstract

Atopic dermatitis (AD) is a common chronic skin disease with a negative influence on adolescent mental health state. We aimed to identify the influencing factors for mental health in adolescents with AD. We used data from the 13th Korean Youth Risk Behavior Web-based Survey (KYRBS) conducted in 2017. KYRBS data were obtained from a stratified, multistage, clustered sample. Participants responded to the question "have you ever been diagnosed with AD by a doctor?" and several yes/no questions about stress, depressive symptoms and suicidal ideation. Among 62 276 participants, the proportion of adolescents with AD was 25.0%. Compared with adolescents without AD, those with AD were significantly more likely to experience stress, depressive symptoms and suicidal ideation (P < 0.001) at rates of 59.1%, 27.8% and 13.9%, respectively. In the multivariate logistic regression model, subjective unhappiness was most strongly associated with stress in subjects with AD (adjusted odds ratio [aOR], 7.34; 95% confidence interval [CI], 5.87-9.18), while depression (aOR, 9.83; 95% CI, 7.85-11.32) and suicidal ideation (aOR, 5.70; 95% CI, 5.01-6.48) were reciprocally the most important risk factors in adolescents with AD. AD in adolescents is associated with a higher prevalence of stress, depressive symptoms and suicidal ideation. It is important for pediatricians to watch for these risks and to screen for suicidality in adolescents with AD.

Eczema is a shared risk factor for anxiety and depression: A meta-analysis and systematic review

“…Our results also show that eczema may be a risk factor for depression, which is consistent with recent studies, although the designs of these studies differed [45][46][47]; however, the relationship between eczema and depression in our present findings differ from those of Slattery et al who conducted a community-based analysis [8]. The possible reasons for this discrepancy include the following: first, the sample size of the study was significantly lower than that of most of the studies included in our meta-analysis; second, their participants were from a specific community, while the participant selection criteria varied greatly among our included studies; and finally, the diagnosis of eczema and depression differed significantly.…”

Health, educational and employment outcomes among children treated for a skin disorder: Scotland-wide retrospective record linkage cohort study of 766,244 children

“…However wider comorbidities exist which we could not adjust for. For example, childhood eczema has also been associated with comorbid allergic rhinitis, hay fever and autoimmune disorders [15][16][17] and even suicidal ideation/behaviour [32][33][34] whilst psoriasis has been associated with obesity, cardiovascular disorders, rheumatoid arthritis, and Crohn's disease [14,[19][20][21] as well as more psychiatric hospitalisations [37]. Therefore, in addition to the direct physical and mental effects associated with skin disorders, it is possible that the greater hospitalisation and mortality observed may be partly attributable to the increased physical and mental comorbidities associated with both eczema and psoriasis over and above those adjusted for in our analyses.…”

Epidemiology of mental health comorbidity in patients with atopic dermatitis: An analysis of global trends from 1998 to 2022

“…Considering our inability to identify any qualified evaluation tool for real-life, retrospective, real-world or computer-based conjoint analysis, we excluded these kinds of analyses from quality evaluations. One case-control study 52 scored less than 5 on the NOS, and seven cross-sectional studies 13,26,[28][29][30]40,51,53 scored 8 or above using the AQHR tool. Details of the quality assessment are presented in Tables S3 and S4.…”