Health foods and medicinal usages of mushrooms

Mizuno, Takashi; Sakai, Tadamoto; Chihara, Goro

doi:10.1080/87559129509541020

Cited by 69 publications

(38 citation statements)

References 9 publications

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“…The use of medicinal mushroom extracts for the medicinal use is recognized and familiar in China, Japan, Korea, Russia and now increasingly in the USA (Mizuno et al, 1995). A number of methods have been developed to extract anti-cancer polysaccharides from mushroom fruitbodies, mycelium and liquid media (Mizuno, 1999).…”

Section: Discussionmentioning

confidence: 99%

Optimization of enzyme assisted extraction of polysaccharides from Poria cocos

Khaskheli¹,

Khaskheli²,

Liu³

et al. 2017

J. Med. Plants Res.

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Water-soluble polysaccharide was isolated from Poria cocus by enzyme-assisted method using orthogonal methodology. By single factor test and orthogonal group, the extraction conditions of watersoluble polysaccharide were investigated, such as liquid-solid ratio, temperature, time and pH. The optimum conditions for single factor were as follows Enzyme concentration (%), Extraction temperature oC, Extraction time/h, Extraction pH. The result revealed that 2% complex enzyme, remained most important factor of polysaccharide extraction, followed by temperature and pH. The liquid-solid ratio was 1:50, temperature was 40°C, time was 3.0 h, and pH was 5. The highest extraction rate of crude polysaccharide remained 4.14%. Results indicated that the complex-enzyme assisted remained best technique for extracting polysaccharide from P. cocus. It proved to be as highly effective as well as energy and time saving extraction techniques.

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Section: Discussionmentioning

confidence: 99%

Optimization of enzyme assisted extraction of polysaccharides from Poria cocos

Khaskheli¹,

Khaskheli²,

Liu³

et al. 2017

J. Med. Plants Res.

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“…The extent of the therapeutic effect by GE-3 was comparable to that by ganciclovir, which was used as a positive control ( Figure 2C). and schizophyllan, which are reported to activate mammalian immune cells (23,24), did not induce muscle contraction. Laminarin, a β-1,3 glucan with low molecular weight, shows little activity for inducing TNF-α production in macrophages (25).…”

Section: Therapeutic Effect Of Ge-3 Against Viral Infectionmentioning

confidence: 99%

Evaluation of innate immune stimulating activity of polysaccharides using a silkworm (Bombyx mori) muscle contraction assay

et al. 2012

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In silkworm larvae, the mature form of paralytic peptide (PP), an insect cytokine, is produced from pro-PP in association with activation of innate immune responses, resulting in slow muscle contraction. We utilized this reaction, muscle contraction in silkworms coupled with innate immunity stimulation, to quantitatively measure the innate immune stimulating activity of various natural polysaccharides. β-Glucan of Gyrophora esculenta (GE-3), fucoidan from sporophyll of Undaria pinnatifida, and curldan induced silkworm muscle contraction. We further demonstrated that GE-3 had therapeutic effects on silkworms infected by baculovirus. Based on these findings, we propose that the silkworm muscle contraction assay is useful for screening substances that stimulate innate immunity before evaluating therapeutic effectiveness in mammals.

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“…(especially G. lucidum) are among the most valuable mushroom fungi in the pharmaceutical industry since they contain several major substances (e.g. polysaccharides and triterpenoids) which demonstrate potent immuno-modulating effects, activation of macrophages, NK and T cells as well as enhanced anti-tumour activity in host-cells (Jong & Birmingham 1992;Mizuno et al 1995;Wasser & Weiss 1999;Gao et al 2003). As more than 700 mushroom species were reported to possess medicinal properties (Chang 1999;Wasser 2002;Dai et al 2009), it is obvious that this group of organisms represents a powerful arsenal of valuable pharmaceutical products or food supplements.…”

Section: Mushrooms As Non-timber Forest Products Exploitation Of Epigmentioning

confidence: 99%

Macrofungi as ecosystem resources: Conservation versus exploitation

Zotti

Persiani

Ambrosio

et al. 2013

Plant Biosystems - An International Journal Dealing with all As

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Fungi are organisms of significant importance not only for the crucial roles they undertake in nature but also for many human activities that are strictly dependent on them. Indeed, fungi possess fundamental positions in ecosystems functioning including nutrient cycles and wood decomposition. As concerns human-related activities, edible and non-edible mushrooms are also involved and/or exploited in forestry, pharmaceutical industry and food production; hence, nowadays they represent a major economic source worldwide. In order to maintain and improve their strategic importance, several conservation strategies, such as habitat preservation, are needed. This article reports several contributions inherent to the relationships between wood-decaying fungi, edible and non-edible mushrooms and their potential exploitation as non-timber forest products and genetic resources.

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Health foods and medicinal usages of mushrooms

Cited by 69 publications

References 9 publications

Optimization of enzyme assisted extraction of polysaccharides from Poria cocos

Optimization of enzyme assisted extraction of polysaccharides from Poria cocos

Evaluation of innate immune stimulating activity of polysaccharides using a silkworm (Bombyx mori) muscle contraction assay

Macrofungi as ecosystem resources: Conservation versus exploitation

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