Health Effects of Drinking Water Produced from Deep Sea Water: A Randomized Double-Blind Controlled Trial

Takeuchi, Hiroaki; Yoshikane, Yu; Takenaka, Hirotsugu; Kimura, Asako; Islam, Jahirul; Matsuda, Reimi; Okamoto, Aoi; Hashimoto, Yusuke; Yano, Rie; Yamaguchi, Koichi; Sato, Shouichi; Ishizuka, Satoshi

doi:10.3390/nu14030581

Cited by 3 publications

(3 citation statements)

References 43 publications

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“…They are freshwater if TDS are less than 1,000ppm, brackish water if TDS less than 1,000-10,000ppm, saline water if TDS less than 10,000-35,000ppm, and hyper-saline water if TDS greater than 35,000. It was reported earlier that deep sea water (DSD)-based drinking water with a hardness level of 1000 enhanced human gut health [7]. Ninety-seven percent of the water in this world is in sea, oceans, and saline groundwater.…”

Section: Drinking Watermentioning

confidence: 99%

Healthy Drinking Water as a Necessity in Developing Countries Like India: A Narrative review

Misra,

Paunikar

2023

Cureus

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Water is an indispensable part of human life. This article is an extensive review that focuses on the importance of water to sustain human life, the necessity of healthy, safe drinking water, and the health hazards of drinking untreated and contaminated water. We drink treated water thinking it to be safe without the knowledge that it, too, has harmful effects. Detrimental health effects due to water chlorination are mentioned in this article. The usage of nanoparticles for the treatment of water is an alternative to chlorination, but they are little in use as they are expensive. Transmission of waterborne diseases through drinking water is widespread in a developing country like India. A list of the pathogens contaminating drinking water is present in the review. Pathogens pollute water, and heavy metals and chemicals from industries, pesticides, pharmaceutical compounds, and radioactive waste also taint it. The harmful effects of metal and chemical toxicities on human health are discussed in this review. The government of India has launched several programmes to ensure clean, safe drinking water for all its residents. The study reflects on the treatment given to individuals suffering from waterborne diseases in India. Significant changes in health status in India have been seen recently after the execution of various government programmes to provide safe, healthy drinking water to all its residents.

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Section: Drinking Watermentioning

confidence: 99%

Healthy Drinking Water as a Necessity in Developing Countries Like India: A Narrative review

Misra,

Paunikar

2023

Cureus

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“…In this concern, resistance training (RT) and specific nutritional supplementation (e.g., calcium, vitamin D, creatine, and magnesium) have elicited positive results as non-pharmacological strategies to prevent and treat the abovementioned long-term conditions [ 10 , 11 , 12 , 13 , 14 ]. Previous studies have documented the direct benefits of liquid mineral-enriched supplementation, such as seawater (SW) on human health (e.g., immunological and gastrointestinal) [ 15 , 16 , 17 ] and performance [ 18 , 19 ]. SW has been mostly studied in aerobic-based sports, as it is depicted in a recent systematic review [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of Microfiltered Seawater Intake and Variable Resistance Training on Strength, Bone Health, Body Composition, and Quality of Life in Older Women: A 32-Week Randomized, Double-Blinded, Placebo-Controlled Trial

Juesas

Gargallo

Gené-Morales

et al. 2023

IJERPH

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The aim was to explore the effects of a 32-week resistance training (RT) intervention with elastic bands with or without microfiltered seawater (SW) supplementation on isokinetic strength, bone mineral density (BMD), body composition, and subjective quality of life in postmenopausal women. Ninety-three untrained women (age: 70.00 ± 6.26 years; body mass index: 22.05 ± 3.20 kg/m2; body fat: 37.77 ± 6.38%; 6.66 ± 1.01 s up-and-go test) voluntarily participated in this randomized, double-blinded, controlled trial. Participants were allocated into four groups (RT+SW, RT+PLA, CON+SW, and CON+PLA). The RT intervention (twice weekly) consisted of different exercises for the whole body performed at submaximal intensities with elastic bands. Both control groups were not involved in any exercise program. A two-way mixed analysis of variance of repeated measures revealed significant improvements in almost all the variables in both intervention groups (p < 0.05). However, significant differences with controls were encountered in isokinetic strength, body fat percentage, and bodily pain. Although the group with SW supplementation obtained greater effect sizes, non-significant differences between both RT groups were observed. In conclusion, the determinant factor of the adaptations seems to be RT rather than SW.

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“…More and more studies have demonstrated that DSW exerts various pharmacological effects, such as the prevention and treatment of hyperlipidemia [ 5 ] and T2DM [ 7 , 8 ], along with improvement of the immune system [ 9 ], anti-tumor properties [ 10 ], and treatment of osteoporosis [ 11 ]. In particular, it has shown promising effects in metabolic diseases [ 5 , 7 , 8 , 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

A Combination of Deep-Sea Water and Fucoidan Alleviates T2DM through Modulation of Gut Microbiota and Metabolic Pathways

Peng

Zhou

et al. 2023

Pharmaceuticals

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Fucoidan and deep-sea water (DSW) are attractive marine resources for treating type 2 diabetes (T2DM). In this study, the regulation and mechanism associated with the co-administration of the two were first studied using T2DM rats, induced by a high fat diet (HFD) and streptozocin (STZ) injection. Results demonstrate that, compared to those with DSW or FPS alone, the orally administered combination of DSW and FPS (CDF), especially the high dose (H-CDF), could preferably inhibit weight loss, decrease levels of fasting blood glucose (FBG) and lipids, and improve hepatopancreatic pathology and the abnormal Akt/GSK-3β signaling pathway. The fecal metabolomics data show that H-CDF could regulate the abnormal levels of metabolites mainly through the regulation of linoleic acid (LA) metabolism, bile acid (BA) metabolism, and other related pathways. Moreover, H-CDF could adjust the diversity and richness of bacterial flora and enrich bacterial groups, such as Lactobacillaceae and Ruminococcaceae UCG-014. In addition, Spearman correlation analysis illustrated that the interaction between the gut microbiota and BAs plays an essential role in the action of H-CDF. In the ileum, H-CDF was verified to inhibit activation of the farnesoid X receptor (FXR)–fibroblast growth factor 15 (FGF15) pathway, which is regulated by the microbiota–BA–axis. In conclusion, H-CDF enriched Lactobacillaceae and Ruminococcaceae UCG-014, thereby changing BA metabolism, linoleic acid metabolism, and other related pathways, as well as enhancing insulin sensitivity and improving glucose and lipid metabolism.

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Health Effects of Drinking Water Produced from Deep Sea Water: A Randomized Double-Blind Controlled Trial

Cited by 3 publications

References 43 publications

Healthy Drinking Water as a Necessity in Developing Countries Like India: A Narrative review

Healthy Drinking Water as a Necessity in Developing Countries Like India: A Narrative review

Effects of Microfiltered Seawater Intake and Variable Resistance Training on Strength, Bone Health, Body Composition, and Quality of Life in Older Women: A 32-Week Randomized, Double-Blinded, Placebo-Controlled Trial

A Combination of Deep-Sea Water and Fucoidan Alleviates T2DM through Modulation of Gut Microbiota and Metabolic Pathways

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