2007
DOI: 10.1038/sj.jes.7500628
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Health effects of air pollution observed in cohort studies in Europe

Abstract: In recent years, several studies in Europe have associated within-city contrasts in air pollution with various health end points including mortality in cohort studies of adults, and respiratory morbidity in cross-sectional and cohort studies of children. Many of these studies have used NO 2 contrasts as the primary exposure variable, which raises the issue of whether such associations are uniquely found for NO 2 per se, or whether NO 2 acts as a surrogate for a complex mixture of combustion pollutants primaril… Show more

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Cited by 83 publications
(78 citation statements)
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References 43 publications
(44 reference statements)
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“…As spatial correlations among PM 2.5 , soot, and NO 2 are generally high, the observed results do not allow disentanglement of the role of these components in causing mortality effects following long-term exposure. The results from these and additional European studies are discussed further in another publication in this special issue (Brunekreef, 2007).…”
Section: Surrogate Measures Of Pollutant Mixturesmentioning
confidence: 86%
“…As spatial correlations among PM 2.5 , soot, and NO 2 are generally high, the observed results do not allow disentanglement of the role of these components in causing mortality effects following long-term exposure. The results from these and additional European studies are discussed further in another publication in this special issue (Brunekreef, 2007).…”
Section: Surrogate Measures Of Pollutant Mixturesmentioning
confidence: 86%
“…Air Pollution -New Developments 6 Nitrogen dioxide (NO 2 ) is one air pollutant frequently used as a surrogate for traffic related pollution in prospective studies, both in adults and in children (Jerrett et al, 2008;Brunekreef, 2007). This is the case because outdoor NO 2 levels correlate well with traffic generated pollutants.…”
Section: Wwwintechopencommentioning
confidence: 89%
“…Much is based on time-series studies -only a few cohort studies consider the morbidity impact of chronic exposure. The literature shows some evidence linking long-term pollution to respiratory problems (Brunekreef, 2007, Götschi et al, 2008, and Schindler et al, 2009. However, none of these studies provided satisfactory ERCs to describe the impact on hospital admissions.…”
Section: Impact On Morbiditymentioning
confidence: 99%
“…Although multi-pollutant studies were preferred for deriving the ERCs, it is difficult to isolate the impacts of individual pollutants completely. Brunekreef (2007) noted that the presence of NO 2 and particulates was often highly correlated.…”
Section: Impact On Morbiditymentioning
confidence: 99%