“…As the COVID-19 pandemic continued in 2022, original research on COVID-19 and reflections on the implications of the pandemic for science and medicine continued to dominate much of the scientific content at JAMA . But we also tackled other major threats to health, including theme issues on gun violence and on health care access and reproductive rights, and the trials, observational studies, and policy analyses we published provided evidence on a range of important issues from the care of critically ill patients to outpatient management of obesity. We also remained committed to the publication of evidence synthesis and guidelines that inform the practice of medicine, publishing 32 reports from the US Preventive Services Task Force, including Recommendation Statements, Evidence Reviews, Modeling Studies, and other articles related to screening or interventions for common diseases and disorders.…”