Health Benefits of Probiotic Consumption

Bastani, Parvin; Akbarzadeh, Fariborz; Homayouni, Aziz; Javadi, Mina; Khalili, Leila

doi:10.1007/978-3-319-25277-3_9

Cited by 6 publications

(4 citation statements)

References 91 publications

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“…In recent years, it has been reported that probiotics, especially lactic acid bacteria, have efficacy relating to the management of diabetes [8]. Probiotics, the live microorganisms, present health benefits to the host, especially when administered in sufficient amounts [9].…”

Section: Introductionmentioning

confidence: 99%

RETRACTED ARTICLE: Probiotic assisted weight management as a main factor for glycemic control in patients with type 2 diabetes: a randomized controlled trial

Khalili

Alipour

Jafarabadi

et al. 2019

Diabetol Metab Syndr

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ObjectivesTo evaluate the effect of Lactobacillus casei 01 on dietary intake, body weight, and glycemic control in patients with T2DM.MethodForty patients with T2DM (n = 20 for each group) were assigned into two groups in present trial. The patients in the probiotic group received a daily capsule containing a minimum of 108 CFU of L. casei 01 for 8 week. The placebo group took capsules filled with maltodextrin for the same time period. Dietary intake questionnaires and anthropometric measurements were collected, and the participants were assessed by an endocrinologist at baseline and at the end of the trial.ResultsLactobacillus casei 01 supplementation significantly decreased total energy, carbohydrate, fat, and protein intake compared with placebo (p = 0.001, p = 0.002, p = 0.009, p = 0.001; respectively). Moreover weight, BMI, and waist circumference were significantly decreased in intervention group compared with placebo group (p < 0.001; p < 0.001; p = 0.029; respectively). In comparison with placebo group serum fetuin-A level, fasting blood sugar, insulin concentration, and insulin resistance were significantly decreased (p = 0.023, p =0.013, p = 0.028; p = 0.007; respectively), and serum SIRT1 level was significantly increased (p = 0.040) in intervention group.ConclusionsLactobacillus casei 01 supplementation affected dietary intake and body weight in a way that improved fetuin-A and SIRT1 levels and glycemic response in subjects with T2DM. Affecting the fetuin-A and SIRT1 levels introduces a new known mechanism of probiotic action in diabetes management.

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Section: Introductionmentioning

confidence: 99%

RETRACTED ARTICLE: Probiotic assisted weight management as a main factor for glycemic control in patients with type 2 diabetes: a randomized controlled trial

Khalili

Alipour

Jafarabadi

et al. 2019

Diabetol Metab Syndr

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“…Moderating gut microbiota by the use of probiotics, prebiotics, and antibiotics could have beneficial effects on glucose metabolism and insulin resistance[4]. Probiotics, the live microorganisms, present health benefits to the host, especially when administered in sufficient amounts[5,6]. Physiologic functions of probiotics would lead to the modulation of gut microbiota and can affect appetite, food intake, body weight, and body metabolic functions through gastrointestinal pathways[7].…”

Section: Introductionmentioning

confidence: 99%

The Effects of Lactobacillus casei on Glycemic Response, Serum Sirtuin1 and Fetuin-A Levels in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial

Khalili

Alipour

Jafarabadi

et al. 2019

ibj

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113

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Background: Type 2 diabetes mellitus (T2DM) is related to the gut microbiota with numerous molecular mechanisms. Modulating the gut microbiota by probiotics could be effective in management of T2DM. The aim of the present trial was to evaluate the effect of Lactobacillus casei on glycemic control and serum sirtuin1 (SIRT1) and fetuin-A in patients with T2DM. Methods: Forty patients with T2DM (n = 20 for each group) were divided into intervention (probiotic) and placebo groups. The intervention group received a daily capsule containing 10 8 cfu of L. casei for eight weeks. The patients in placebo group took capsules containing maltodextrin for the same time duration. Anthropometric measurements, dietary intake questionnaires, and blood samples were collected, and the patients were assessed by an endocrinologist at the beginning and at the end of the trial. Results: Fasting blood sugar, insulin concentration, and insulin resistance significantly decreased in probiotic group compared with placebo group (-28.

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“…13,14 Probiotik adalah mikroorganisme hidup yang jika diberikan dengan jumlah yang adekuat dapat memberikan manfaat kesehatan bagi organisme lain/inangnya. 15 Probiotik bisa ditemukan dalam produk-produk makanan dan minuman, misalnya yoghurt, susu, tempe, acar, kefir dan juga dalam bentuk suplemen. Penelitian tentang mikrobiota usus menunjukkan bahwa profil komunitas bakteri merupakan faktor utama yang berkontribusi terhadap perkembangan DMT2, selain faktor genetik dan lingkungan.…”

Section: Pendahuluanunclassified

Pengaruh Probiotik Dalam Menurunkan Kadar Gula Darah Pada Penderita Diabetes Melitus Tipe 2

Jainata

Utama

Desmawati

2022

JIKESI

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Latar Belakang Diabetes Melitus Tipe 2 (DMT2) adalah bentuk diabetes yang paling umum, terhitung sekitar 90% dari semua kasus diabetes. Perubahan komposisi mikrobiota pada kolon berkontribusi terhadap perkembangan DMT2. Memodulasi mikrobiota usus dengan probiotik efektif dalam pengelolaan DMT2. Objektif Tinjauan sistematis ini dilakukan untuk mengetahui pengaruh probiotik dalam menurunkan kadar gula darah penderita diabetes melitus tipe 2. Metode Artikel dikumpulkan dari tiga pangkalan data, yaitu Pubmed, Cochrane dan Turning Research Into Practice (TRIP) dengan menggunakan kata kunci Probiotics, Lactobacillus sp, Bifidobacterium sp, Blood sugar, Type 2 diabetes Mellitus. Pencarian artikel ini dilakukan secara online pada bulan November 2020. Artikel yang didapatkan harus memenuhi kriteria inklusi dan eksklusi yang telah didapatkan. Hasil Dari 108 artikel yang didapatkan hanya 12 artikel yang memenuhi kriteria inklusi dan eksklusi. Sebelas artikel melaporkan pengaruh probiotik pada HbA1c, terdapat tujuh penelitian yang mengalami penurunan kadar HbA1c secara signifikan, tiga penelitian tidak mengalami penurunan yang signifikan dan satu penelitian melaporkan peningkatan kadar HbA1c setelah intervensi probiotik. Dua belas artikel melaporkan pengaruh probiotik pada GDP, tujuh penelitian melaporkan penurunan GDP secara signifikan dan lima penelitian lainnya tidak terjadi penurunan signifikan GDP dibandingkan kontrol setelah intervensi probiotik. Kesimpulan Penurunan kadar Gula Darah Puasa (GDP) terjadi secara signifikan setelah intervensi probiotik pada tujuh penelitian dan lima penelitian lainnya melaporkan terjadi penurunan GDP yang tidak signifikan. Penurunan kadar HbA1c terjadi secara signifikan pada tujuh penelitian, tiga penelitian tidak mengalami penurunan yang signifikan dan satu penelitian melaporkan peningkatan kadar HbA1c setelah intervensi probiotik dibandingkan kontrol.

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Health Benefits of Probiotic Consumption

Cited by 6 publications

References 91 publications

RETRACTED ARTICLE: Probiotic assisted weight management as a main factor for glycemic control in patients with type 2 diabetes: a randomized controlled trial

RETRACTED ARTICLE: Probiotic assisted weight management as a main factor for glycemic control in patients with type 2 diabetes: a randomized controlled trial

The Effects of Lactobacillus casei on Glycemic Response, Serum Sirtuin1 and Fetuin-A Levels in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial

Pengaruh Probiotik Dalam Menurunkan Kadar Gula Darah Pada Penderita Diabetes Melitus Tipe 2

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