Health Benefits of Manuka Honey as an Essential Constituent for Tissue Regeneration

Niaz, Kamal; Maqbool, Faheem; Bahadar, Haji; Abdollahi, Mohammad

doi:10.2174/1389200218666170911152240

Cited by 25 publications

(26 citation statements)

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“…Honey has been used in wound therapy for several decades. Recent studies have shown that honey has an inhibitory effect on approximately 60 bacteria species and acts against aerobes and anaerobes (15). In addition, it has antifungal action against Aspergillus species, yeast and dermatophytes (16).…”

Section: Discussionmentioning

confidence: 99%

“…In addition, it has antifungal action against Aspergillus species, yeast and dermatophytes (16). Manuka honey, produced in New Zealand, contains rich chemical ingredients that have, among others, antioxidant effects that aid in rapid wound healing and faster tissue regeneration (15). The advantages of honey include a high osmotic effect on wounds, which inhibits microbial growth, allowing creation of a perfect osmotic gradient that would mop up exudate from the wound, enabling faster healing.…”

Section: Discussionmentioning

confidence: 99%

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Wound dressing techniques and costs at a county hospital

Odhiambo¹,

Omondi²,

Magak³

2019

Ann Afr Surg.

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Background: Wound management is one of the commonest procedures conducted in surgical departments across health facilities in Kenya. Objective: This study aimed at exploring wound dressing techniques used at Migori County Referral Hospital (MCRH) and the cost of treatment to patients. Methods: Convenience sampling was used to select inpatients presenting with wounds undergoing treatment at the time of recruitment. Five patients (2 male and 3 female) were enrolled after obtaining informed consents. Wounds were examined during cleaning and dressing and healing process follow-ups made. Selection of wound dressing technique was done by the primary clinicians with no bias from the research team. Results: One patient's wound was an open fracture resulting from a road traffic accident; three patients had pyomyositis following thorn pricks; and the last patient's was sustained following a blast injury. Wound management methods employed at MCRH included cleaning with vinegar, irrigation with normal saline, dressing with honey, and improvised negative pressure wound therapy. Total cost incurred was affordable to patients, and ranged between Kenya shillings 100-360 (USD 1-3.60) weekly. Conclusion: Wound management techniques at MCRH were effective and affordable. Additional studies with a larger sample size are recommended.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Wound dressing techniques and costs at a county hospital

Odhiambo¹,

Omondi²,

Magak³

2019

Ann Afr Surg.

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“…Manuka ( Leptospermum scoparium ) honey (MH) is broadly known for its therapeutic properties in epithelial regeneration and wound‐healing . Numerous in‐vitro studies have demonstrated MH and its active component, methylglyoxal (MGO), activity against both the planktonic and biofilms forms of a wide range of bacteria, including S aureus (methicillin‐sensitive S aureus and MRSA) and P aeruginosa .…”

Section: Resultsmentioning

confidence: 99%

Future topical medications in chronic rhinosinusitis

Miyake

Bleier

2019

Int Forum Allergy Rhinol

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Background:Research has progressed rapidly in recent decades to be er understand the etiopathogenesis and management paradigms of chronic rhinosinusitis (CRS). Although oral antibiotics o en mitigate symptoms in acute CRS exacerbations, eradication of polymicrobial biofilms and multidrug-resistant bacteria remains a challenge. The goal of this review is to summarize and discuss the potential and pitfalls of topical medications in the treatment of CRS. Methods:A related literature review was performed using PubMed and Scopus, with only the English database included. Results:The main therapies were selected and separated in sections. Details regarding future topical treatments of CRS were summarized and discussed. Conclusion:The ease of access of the sinonasal mucosa positions CRS as a disease with high potential for local topical treatment. The ultimate adoption of topical agents will require continued expansion of our understanding of novel local targets in CRS as well as improved methods to deliver and retain the drug of interest at the site of activity. C 2019 ARS-AAOA, LLC.

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“…It has been observed that dressing with honey reduces odor in infected wounds. There are many literatures suggesting that honey can be used effectively as a dressing for wounds, burns, and skin ulcers [5,6,9,20,21]. Not all honeys have the same effect.…”

Section: Groupmentioning

confidence: 99%

“…Since manuka honey has biological activities such as antioxidant, antimicrobial and antiproliferative, scientists still study on the Manuka honey [21].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Manuka Honey (Manuka Nd, G) and Etacridine Lactate (Rivanol) Applications in the Treatment of Infected Wounds in Cats

Kemiksiz

Akçay

2019

Acta Scientiae. Vet.

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Background: Ethacridine lactate (Rivanol) has been used as an antibacterial drug in the treatment of infected wounds for many years. Although Manuka honey has been used in the treatment of burns, ulcers and infected wounds in human medicine for many years, its use in veterinary medicine is new. Manuka honey has been found to provide rapid cicatrization and lower chronic pain levels, to prevent bad odor, and has antibacterial properties. The aim of this study was to compare the effects of Etacridine lactate and Manuka honey in the treatment of infected wounds in cats.Materials, Methods & Results: In this study, 32 cats, with infected wounds in different areas on their body, were used. Cats were divided into two groups. The Rivanol group (n = 16) consisted of 6 female and 10 male cats aged 4 ± 3 years from different breeds and in several weights. Manuka group (n = 16) consisted of 7 male and 9 female cats of different breeds and weight and aged 4 ± 2 years. Rivanol was applied to the first group and Manuka honey (Manuka Nd, G) was applied to the second group. First measurements were recorded after the surgical debridement of the wound area. Four measurements were made every 3 days. The size (length - width) of the wounds was measured and recorded. Parenteral Marbofloxacin was administered orally in all cases. In order to prevent the contact of the cases with the dressing, the collar was worn. In the Rivanol group, when the first measurement values (length: 4.29 ± 2.78 cm, width: 2.13 ± 0.58 cm) and the 4th measurement values (length: 2.21 ± 1.37 cm, width: 1.06 ± 0.41 cm) were compared, there was a decrease in the wound size. In the Manuka group, when the first measurement values (length 2.84 ± 1.51 cm, width: 2.01 ± 1.03cm) and the 4th measurement values (length: 1.42 ± 1.10 cm, width: 0.90 ± 0.72cm) were compared, the wound sizes were diminished as in the Rivanol group. In all measurement days, the differences between of Rivanol and Manuka groups concerning the width, length and wound sizes were not statistically significant (P > 0.05). Wound size, length and width showed a linear decrease over the measurement days. These decreases were similar in Rivanol and Manuka group. There was no statistically significant difference between Rivanol (12.44 ± 3.74 days) and Manuka (12.44 ± 4.68 days) groups over the cicatrization period (P > 0.05).Discussion: Rivanol and Manuka honey were effective in wound healing. Although there were no differences between the two groups, the wound sizes decreased in each measurement of the wounds. A moist environment was formed on the wound, debrideman accelerated and granulation tissue formation was encouraged with the application of both topical agents. Therefore, it was considered that wound healing in our cases was successful. It has been found that honey is frequently applied in wound treatment and in many areas in human medicine. However, in the field of veterinary medicine, there were few investigations. In the treatment of infected wounds of cats, it was determined that the application of Rivanol and Manuka honey yielded similar results in terms of time and there was no statistically significant difference. Manuka honey was found to be an alternative to Rivanol in the treatment of infected cat wounds. Manuka honey preparations (pad or pomade) were preferred because of the ease of use. In order to determine the efficacy of manuka honey in wound healing, it was thought that many further clinical or experimental studies should be carried out using microbiological, biochemical and histopathological parameters.

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Health Benefits of Manuka Honey as an Essential Constituent for Tissue Regeneration

Cited by 25 publications

References 0 publications

Wound dressing techniques and costs at a county hospital

Wound dressing techniques and costs at a county hospital

Future topical medications in chronic rhinosinusitis

Comparison of Manuka Honey (Manuka Nd, G) and Etacridine Lactate (Rivanol) Applications in the Treatment of Infected Wounds in Cats

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