2017
DOI: 10.1016/j.jcm.2016.08.008
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Health Benefits of Dietary Whole Grains: An Umbrella Review of Meta-analyses

Abstract: This review suggests that there is some evidence for dietary whole grain intake to be beneficial in the prevention of type 2 diabetes, cardiovascular disease, and colorectal, pancreatic, and gastric cancers. The potential benefits of these findings suggest that the consumption of 2 to 3 servings per day (~45 g) of whole grains may be a justifiable public health goal.

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Cited by 105 publications
(83 citation statements)
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References 36 publications
(37 reference statements)
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“…However, based on a 2014 meta‐analysis of randomised trials, fruit and vegetable intake may not relate to weight loss, because the most important factor for weight loss is energy restriction. Simlarly, low‐fat dairy products, legumes and whole grains have negatively associated with obesity in observational studies. Effects of these foods on weight maintenance may be due to low energy density, high fibre intake, protein content or micronutrients like calcium .…”
Section: Discussionmentioning
confidence: 99%
“…However, based on a 2014 meta‐analysis of randomised trials, fruit and vegetable intake may not relate to weight loss, because the most important factor for weight loss is energy restriction. Simlarly, low‐fat dairy products, legumes and whole grains have negatively associated with obesity in observational studies. Effects of these foods on weight maintenance may be due to low energy density, high fibre intake, protein content or micronutrients like calcium .…”
Section: Discussionmentioning
confidence: 99%
“…Whole grain flours are nutritionally superior to refined flours, since they contain the fibre, vitamins, minerals and phytochemicals that are mainly present in the bran and germ and have been reported to contribute to positive health effects [1]. Recent meta-analyses provide evidence of an inverse association between whole grain intake and risk of non-communicable diseases including cardiovascular disease, type 2 diabetes mellitus, certain cancers and obesity [2,3]. Higher whole grain intake has also been reported to improve fertility health parameters, notably increasing the probability of embryo implantation and live birth among women undergoing in vitro fertilisation [4].…”
Section: Introductionmentioning
confidence: 99%
“…Other studies also report adverse effects on osteoporosis 35 and hyperlipidemia 36 , insulin resistance 37 , glucose intolerance 38 and hepatic steatosis 39 .…”
Section: Discussionmentioning
confidence: 99%
“…The study by Garbow et al 39 showed that in C57BL/6J mice, the ketogenic diet led to the development of glucose intolerance, endoplasmic reticulum stress, steatosis, cell damage and accumulation of macrophages in relation to traditionally Western diets (high content of simple carbohydrates and saturated fat).…”
Section: Discussionmentioning
confidence: 99%