Health Benefits of Dietary Fiber for the Management of Inflammatory Bowel Disease

Yusuf, Kafayat; Saha, Subhrajit; Umar, Shahid

doi:10.3390/biomedicines10061242

Cited by 30 publications

(23 citation statements)

References 99 publications

(169 reference statements)

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“…Over time, our growing comprehension of the significance of fiber for gastrointestinal health has highlighted the importance of IBD patients achieving an adequate dietary intake as well [ 4 , 47 ]. Although research studies on the role of fiber in the prevention and treatment of IBD in humans are limited [ 48 ], existing intervention trials have shown that dietary fibers can improve IBD symptoms [ 49 ], enhance health-related quality of life [ 50 ], balance inflammation [ 47 ], modulate immune responses [ 51 ], and help mitigate dysbiosis by restoring the gut microbiome [ 52 ]. Dietary fibers mediate these beneficial effects though byproducts of dietary fermentation of MAC, principally SCFA [ 53 , 54 ], and also by preserving the mucus layer barrier by promoting mucus synthesis and secretion [ 16 , 55 ].…”

Section: Nutritional Recommendations In Ibd About Fiber Intakementioning

confidence: 99%

Dietary Fiber in Inflammatory Bowel Disease: Are We Ready to Change the Paradigm?

Loy,

Petronio,

Marcozzi

et al. 2024

Nutrients

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Accumulating evidence from pre-clinical and clinical studies demonstrate the benefit of dietary fibers for inflammatory bowel disease (IBD). However, the majority of patients avoid or limit their consumption to manage their symptoms during the active and remission phases, although limited research supports these long-term dietary habits. Although recent evidence-based dietary guidelines highlight the importance of promoting an adequate intake of dietary fiber in IBD patients, intervention trials have not yet clearly clarified the quality and quantity of dietary fiber that should be consumed to be equally tolerated by and provide benefit for patients with IBD. This narrative review describes dietary fibers and their characteristics, analyzes the real-word studies on the impact of dietary fiber consumption in IBD in different clinical settings, and concludes with potential future directions in fiber research, focusing on the real-world needs of characterizing the consumption of fiber-rich foods and promoting their adequate intake.

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Section: Nutritional Recommendations In Ibd About Fiber Intakementioning

confidence: 99%

Dietary Fiber in Inflammatory Bowel Disease: Are We Ready to Change the Paradigm?

Loy,

Petronio,

Marcozzi

et al. 2024

Nutrients

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“…IBD is a global healthcare problem with a sustained increasing incidence, affecting millions of people worldwide, all ages and genders [ 55 , 56 ]. It includes two major forms, Ulcerative Colitis, and Crohn’s Disease, which are distinct chronic inflammatory disorders of the gastrointestinal tract with differences in the pathology and clinical characteristics [ 57 , 58 ]. Ulcerative Colitis is typified by mucosal inflammation and is limited to the colon.…”

Section: Role Of Hydroxytyrosol In Ibdsmentioning

confidence: 99%

Hydroxytyrosol and Its Potential Uses on Intestinal and Gastrointestinal Disease

Arangia

Marino

Impellizzeri

et al. 2023

IJMS

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In recent years, the phytoconstituents of foods in the Mediterranean diet (MD) have been the subject of several studies for their beneficial effects on human health. The traditional MD is described as a diet heavy in vegetable oils, fruits, nuts, and fish. The most studied element of MD is undoubtedly olive oil due precisely to its beneficial properties that make it an object of interest. Several studies have attributed these protective effects to hydroxytyrosol (HT), the main polyphenol contained in olive oil and leaves. HT has been shown to be able to modulate the oxidative and inflammatory process in numerous chronic disorders, including intestinal and gastrointestinal pathologies. To date, there is no paper that summarizes the role of HT in these disorders. This review provides an overview of the anti-inflammatory and antioxidant proprieties of HT against intestinal and gastrointestinal diseases.

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“…The anti-inflammatory effect facilitated by the conversion of dietary fiber to short-chain fatty acids (SCFA) by intestinal microbiota has been discussed at length by the recent literature [ 80 , 81 ]. In fact, the inflammation-mediating effects of SCFAs alongside indole compounds and dietary omega-3 polyunsaturated fatty acids has also been attributed to interactions between the gut microbiota and macrophages [ 82 ].…”

Section: Specific Dietary Interventionsmentioning

confidence: 99%

Dietary Exposures and Interventions in Inflammatory Bowel Disease: Current Evidence and Emerging Concepts

et al. 2023

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Diet is intimately linked to the gastrointestinal (GI) tract and has potent effects on intestinal immune homeostasis. Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the GI tract. The therapeutic implications of diet in patients with IBD have received significant attention in recent years. In this review, we provide a contemporary and comprehensive overview of dietary exposures and interventions in IBD. Epidemiological studies suggest that ultra-processed foods, food additives, and emulsifiers are associated with a higher incidence of IBD. Exclusion and elimination diets are associated with improved symptoms in patients with IBD, but no effects on objective markers of inflammation. Specific dietary interventions (e.g., Mediterranean, specific carbohydrate, high fiber, ketogenic, anti-inflammatory diets) have been shown to reduce symptoms, improve inflammatory biomarkers, and quality of life metrics to varying degrees, but these studies are limited by study design, underpowering, heterogeneity, and confounding. To date, there is no robust evidence that any dietary intervention alone may replace standard therapies in patients with IBD. However, diet may play an adjunct role to induce or maintain clinical remission with standard IBD therapies. The results of novel dietary trials in IBD such as personalized fiber, intermittent fasting, and time-restricted diets are eagerly awaited.

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Health Benefits of Dietary Fiber for the Management of Inflammatory Bowel Disease

Cited by 30 publications

References 99 publications

Dietary Fiber in Inflammatory Bowel Disease: Are We Ready to Change the Paradigm?

Dietary Fiber in Inflammatory Bowel Disease: Are We Ready to Change the Paradigm?

Hydroxytyrosol and Its Potential Uses on Intestinal and Gastrointestinal Disease

Dietary Exposures and Interventions in Inflammatory Bowel Disease: Current Evidence and Emerging Concepts

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