Health Behaviors in Cervical Cancer Survivors and Associations with Quality of Life

Iyer, Neel S.; Osann, Kathryn; Hsieh, Susie; Tucker, Jo A.; Monk, Bradley J.; Nelson, Edward L.; Wenzel, Lari

doi:10.1016/j.clinthera.2016.02.006

Cited by 28 publications

(24 citation statements)

References 37 publications

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“…Therefore, poorer emotional functioning and poorer mental health have been associated with higher FCR [ 17 ]. Concerning factors related to anxiety, Iyer et al [ 29 ] found that CCSs who exercised at least 3 hours per week experienced less depression and anxiety. Furthermore, Kim et al [ 2 ] reported anxiety in CCSs was commonly associated with financial difficulty, poor body image, sexual inactivity, low existential well-being and insomnia.…”

Section: Discussionmentioning

confidence: 99%

Fear of cancer recurrence and its predictors among cervical cancer survivors

et al. 2017

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ObjectiveTo identify the characteristics of fear of cancer recurrence (FCR) in cervical cancer survivors (CCSs) and investigate the relationship of FCR with demographic and medical characteristics, level of quality of life (QOL), and psychological distress. We also aimed to determine the predictors of FCR.MethodsThe short version of the Fear of Progression Questionnaire (FoP-Q-SF), the Hospital Anxiety and Depression Scale (HADS), and the Functional Assessment of Cancer Therapy-Cervical (FACT-Cx) questionnaire were administered to 699 CCSs who had complete treatment at Songklanagarind Hospital between 2006 and 2016. Analysis was performed to determine potential predictors associated with FCR.ResultsAmong the 12 items of the FoP-Q-SF, the 3 greatest fears were 1) worrying about what would happen to their family; 2) being afraid of pain; and 3) fear of disease progression. The prevalences of anxiety and depression disorder were 20.46% and 9.44%, respectively. CCSs who had FCR at the 5th quintile were more likely to have medical co-morbidities, low FACT-Cx scores in all domains and a high HADS scores (anxiety and depression disorder). Multivariate analysis showed that only anxiety disorder (odds ratio [OR]=4.99; p<0.001) and low FACT-Cx score (total) (OR=6.14; p<0.001) were identified as independent predictors for FCR at the 5th quintile.ConclusionFCR is an important problem in cervical cancer which should be addressed during post-treatment care. Only anxiety disorder and low QOL were independently associated with high FCR.

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Section: Discussionmentioning

confidence: 99%

Fear of cancer recurrence and its predictors among cervical cancer survivors

et al. 2017

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“…12 Health-related behaviors, including smoking, lack of physical activity, and increased alcohol consumption, also contribute to decreased overall survival and quality of life in cervical cancer survivors. As noted by Osann et al, 13 prospective studies have shown that cervical cancer survivors who are smokers have more recurrences than do nonsmokers with significantly shorter overall survival.…”

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confidence: 81%

“…Iyer et al 13 undertook their study to describe the prevalence of health behaviors, specifically, physical activity, smoking, and alcohol consumption, among cervical cancer survivors, with the ultimate goal of examining the associations between health behaviors and quality of life. Cervical cancer survivors were recruited to participate in a randomized psychosocial by-telephone counseling trial.…”

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confidence: 99%

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Cervical Cancer: The Next Generation of Prevention, Detection, and Treatment

Duska

2016

Clinical Therapeutics

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Cervical cancer remains an important problem in the United States and, more significantly, the world, despite the US Food and Drug Administration's approval of the first in-human papillomavirus (HPV) vaccine in 2006. In the United States in 2016, even with mature screening programs, an estimated 12,990 women will be diagnosed with cervical cancer and 4120 will die from the disease. 1 Worldwide, these numbers are more staggering: Cervical cancer is the fourth most frequent cancer in women, with an estimated 530,000 new cases and 270,000 deaths in 2012. 2 The treatment of cervical cancer in almost all cases will result in a loss of future fertility, as well as other significant treatment sequelae leading to a decreased quality of life.Unfortunately, cervical cancer continues to be a cancer of young women; in fact, as noted by Pelkofski et al 3 in this issue of Clinical Therapeutics, cervical cancer is the most common gynecologic malignancy in women o35 years of age. Those young women who develop cervical cancer, by virtue of their young age and the trend in the United States to delay childbearing, are at particular risk for loss of fertility, with 22% in the report from Pelkofski et al 3 having never been pregnant.In the series from Pelkofski et al, the "very young" patients (25 years or younger) were compared to the socalled "young" patients (26-35 years). While there was no difference in progression-free or overall survival between these two groups, the investigators did make some interesting observations. First, 5 of the 17 "very young" women with cervical cancer were aged 20 years or younger. It is of interest that all 5 of these women were diagnosed by Pap smear (author, personal communication), a screening procedure for which they would not be eligible under the current guideline. 4 While concerning, this finding must be placed into perspective: This is a very small-scale experience in a rural and underserved population from two mid-Atlantic university-based practices, and the findings contradict those from a larger-scale population-based study that suggests the that rate of cervical cancer in women under age 21 years is "vanishingly small." 5 There are no data to suggest that screening in women o21 years of age affects future rates of pre-invasive disease, and screening this population may result in unnecessary procedures because younger women are more likely to clear pre-invasive disease. 6 Nonetheless, the relatively large number of young women in this series merits further consideration in future, larger-scale studies. Second, the rate of small cell carcinoma, a subtype associated with a very poor prognosis, was 4.4%, which is greater than expected in the overall cervical cancer group (expected, o3%). 7 Third, and perhaps most important, the 5-year survival rate in the entire patient group (women aged 35 years or under) in the study by Pelkofski et al 3 was surprisingly low. Despite the fact that over 80% of women had early stage disease, the 5-year survival rate in the entire cohort was 42.1%, with a 5-y...

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“…A separate domain of surveys concerning CaCx is presented by studies addressing the issues of quality of life (QoL), information needs, sexuality, and other problems in patients with cervical cancer or its precursor, who had undergone the treatment [45][46][47][48][49].…”

Section: Survey As An Instrument To Get Informationmentioning

confidence: 99%

Results of a Survey Concerning Cervical Cancer Risk Factors among Women in Western Kazakhstan

Balmagambetova¹,

Koyshybaev²,

Kanshaiym³

et al. 2019

Current Perspectives in Human Papillomavirus

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During 2014-2017, a survey concerning risk factors for cervical cancer involving 1166 clinically healthy women and 65 having CaCx was conducted in Western Kazakhstan. Only 34.7% of interviewees constantly participated in state-sponsored screening program, while 37.3% ignored screening in free state-sponsored clinics. Favorable attitude toward vaccination stated 22.9% of the respondents, whereas 38.8% knew nothing, and 33.6% could not clarify their position in this issue. Education is a key factor for better perception of preventive measures-69.2% of the respondents with higher education are aware of vaccination (p ≤ 0.00001, Cramer's V 0.18, χ 2-23.1). Social profiles of HPV-infected and CaCx-diseased women differ significantly and, mainly, by standard of living and occupational status. The likelihood of the CaCx onset in Western Kazakhstan decreased by 14 times at relatively high standard of living (OR 0.0713, p = 0.024) and by 3.3 times provided at least irregular participation in screening (OR 0.3384, p = 0.0304). Overall, the findings are quite able to contribute to an understanding why women become affected by CaCx. Low standard of living due to lack of education, low attendance of screening, and low awareness on preventive measures-all these reasons are interacted and constitute a set of universal triggers for vulnerability toward CaCx.

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Health Behaviors in Cervical Cancer Survivors and Associations with Quality of Life

Cited by 28 publications

References 37 publications

Fear of cancer recurrence and its predictors among cervical cancer survivors

Fear of cancer recurrence and its predictors among cervical cancer survivors

Cervical Cancer: The Next Generation of Prevention, Detection, and Treatment

Results of a Survey Concerning Cervical Cancer Risk Factors among Women in Western Kazakhstan

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