Health Aspects of Antioxidant Nutrients: A Consice Update

Waly, Mostafa I.

doi:10.23880/oajar-16000102

Cited by 3 publications

(3 citation statements)

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“…Plant-derived foods-i. e., fruits, vegetables, cereal grains, and seeds-contain natural antioxidants that can confer on the body a significant protection against ROS-induced oxidative stress (Waly et al, 2016). Mediterranean-style diets have been known cause a significant decline in cardiovascular diseases through an intervention in lipoprotein oxidation with a consequent reduction in oxidative stress.…”

Section: Introductionmentioning

confidence: 99%

Preparation of soy protein hydrolysates with antioxidant activity by using peptidases from latex of Maclura pomifera fruits

Jara

Liggieri²,

Bruno³

2018

Food Chemistry

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A partially purified proteolytic extract prepared from Maclura pomifera latex was employed in hydrolyzing a soybean-protein isolate (4.2 mg/mL). The hydrolysis-product formation, monitored by tricine-sodium-dodecyl-sulfate-polyacrylamyde-gel electrophoresis and reverse-phase high-performance liquid chromatography, indicated that after 10 min of reaction the main soybean proteins disappeared. The maximum degree of hydrolysis was 36.2% after a 180-min digestion. The 90-min hydrolysate presented an IC of 31.6 ± 0.2 µg/mL, and a trolox equivalent antioxidant capacity of 157.6 and 176.9 µmoles TE per g of peptide determined by two different methods. Analysis by matrix-assisted-laser-desorption-ionization-time-of-flight mass spectrometry (MALDI-TOF MS), followed by the application of bioinformatics tools, enabled the deduction of fourteen theoretical peptide sequences containing antioxidant amino acids at >60%, none of which sequences had been previously reported as antioxidants. Finally, we consider that this 90-min hydrolysate would constitute a promising ingredient in the manufacture of functional foods.

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Section: Introductionmentioning

confidence: 99%

Preparation of soy protein hydrolysates with antioxidant activity by using peptidases from latex of Maclura pomifera fruits

Jara

Liggieri²,

Bruno³

2018

Food Chemistry

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“…Hydrogen peroxide (H2O2) is a well-known ROS that is formed during normal metabolism, where it is produced in the brain during the catalytic degradation of neurotransmitters such as dopamine and it is estimated that 3% of body's hemoglobin is auto oxidized daily to produce H2O2 (Sakihama et al, 2002). GSH is the primary redox buffer in all human neuronal cells and when two molecules of GSH combine to form oxidized glutathione (GSSH), two reducing equivalents of H+ are made available for the quenching of ROS, thereby protecting human cells from oxidative damage (Waly, 2016).…”

Section: Resultsmentioning

confidence: 99%

Investigation on Peroxidase Activity of Graviola (Annona muricata L.) at Different Stages of Fruit Development

Pandarinathan¹

2019

Int.J.Curr.Microbiol.App.Sci

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“…Hydrogen peroxide (H2O2) is a well-known ROS that is formed during normal metabolism, where it is produced in the brain during the catalytic degradation of neurotransmitters such as dopamine and it is estimated that about 3 % of body's hemoglobin is autoxidized daily to produce H2O2 [11]. GSH is the primary redox buffer in all human neuronal cells, and when two molecules of GSH combine to form oxidized glutathione (GSSG), two reducing equivalents of H + are made available for the quenching of ROS, thereby protecting human cells from oxidative damage [12]. GSH can also combine with xenobiotics and heavy metals resulting in an increase in their rate of excretion and provides an important mode of detoxification [13].…”

Section: Introductionmentioning

confidence: 99%

Phytonutrients Potential Properties of Graviola Leaves Extract

Waly¹

2018

OAJAR

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Recent studies indicated that regular consumption of antioxidant rich foods reduce cellular oxidative stress and protect against health related problems. Annona muricata, is a tropical fruit, commonly known as Graviola, which has been identified as a rich source of bioactive compounds and is considered as an integral part of folklore medicine. The use of Graviola leaves as a therapeutic agent is recently accelerated, yet there is scarce scientific evidence justifying its use. This study aimed to assess the in vitro antioxidant properties and phytonutrients content of the Omani cultivated Graviola leaves. Our study revealed that Graviola leaves extract is rich in phytonutrients content (The total phenolic content was 16.82 mg Gallic acid equivalent (GAE)/g dry solid and the total flavonoid content was 7.79 mg Catechin equivalent (CE)/ g dry solid) and acted as a potent free radical scavenger and provided protection against H2O2-induced oxidative stress.

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Health Aspects of Antioxidant Nutrients: A Consice Update

Cited by 3 publications

References 0 publications

Preparation of soy protein hydrolysates with antioxidant activity by using peptidases from latex of Maclura pomifera fruits

Preparation of soy protein hydrolysates with antioxidant activity by using peptidases from latex of Maclura pomifera fruits

Investigation on Peroxidase Activity of Graviola (Annona muricata L.) at Different Stages of Fruit Development

Phytonutrients Potential Properties of Graviola Leaves Extract

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