Introduction: Wound closure is a part of any surgical procedure and the objective of laceration repair or incision closure is to approximate the edges of a wound so that natural healing process takes place. Over the years new biomaterials have been used as an alternate to conventional suture materials. Cyanoacrylate bio adhesives are one among them. They carry the advantage of rapid application, patient comfort, resistance to infection, hemostatic properties, and no suture removal anxiety. Hence this study was undertaken to study the effect of long chain cyanoacrylate as an adhesive for intraoral wound closure and also to explore its hemostatic and antibacterial effects.The aim of this study is to compare the efficacy of cyanoacrylate and black braided silk for the closure of surgical incision after removal of impacted third molars. Results: The reviews found some clinical evidence that, there is significant difference between sutures and cyanoacrylate on postoperative pain following mandibular third molar surgery. There is also significant difference between sutures and cyanoacrylate on haemostasis following mandibular third molar surgery.
Conclusion:The clinical evidence in this review is adequate to state that, there is a difference in postoperative pain and haemostasis following mandibular third molar surgery between black braided silk and cyanoacrylate.