Healing at implants placed in bone of different morphology: an experimental study in dogs

Caroprese, Marino; Soldini, Claudio; Ricci, Sara; Rea, Massimiliano; Lang, Niklaus P.; Botticelli, Daniele

doi:10.1111/clr.12905

Cited by 3 publications

(3 citation statements)

References 14 publications

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“…These results support the preclinical evidence of the good osteoproperties of OGI surface by Caroprese et al [ 32 ] that analysed in the osseointegration of implants with OGI surface installed using a standard bed preparation in sites of different bone morphology. Results confirmed that the final insertion torque was 50–55 Ncm at the premolar and 30–35 Ncm at the molar sites.…”

Section: Discussionsupporting

confidence: 90%

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The Biological Properties of OGI Surfaces Positively Act on Osteogenic and Angiogenic Commitment of Mesenchymal Stem Cells

et al. 2017

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Osteogenesis process displays a fundamental role during dental implant osteointegration. In the present work, we studied the influence of Osteon Growth Induction (OGI) surface properties on the angiogenic and osteogenic behaviors of Mesenchymal Stem cells (MSC). MSC derived from dental pulp and HUVEC (Human Umbilical Vein Endothelial Cells) were grown in on OGI titanium surfaces, and cell proliferation and DNA synthesis were evaluated by MTT [3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide] test and DNA quantification. Gene expression has been performed in order to evaluate the presence of mRNA related to endothelial and osteogenesis markers. Moreover, morphological and biochemical analyses of osteogenesis commitments has been performed. On OGI surfaces, MSC and HUVEC are able to proliferate. Gene expression profiler confirms that MSC on OGI surfaces are able to express endothelial and osteogenic markers, and that these expression are higher compared the expression on control surfaces. In conclusion On OGI surfaces proliferation, expression and morphological analyses of angiogenesis-associated markers in MSC are promoted. This process induces an increasing on their osteogenesis commitment.

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Section: Discussionsupporting

confidence: 90%

“…This could reduce biocompatibility. However, OGI Titanium (Ti) surface microarchitecture has been shown to increase osteoblast differentiation [ 28 , 29 , 30 , 31 , 32 ] by our previous publication.…”

Section: Discussionmentioning

confidence: 99%

The Biological Properties of OGI Surfaces Positively Act on Osteogenic and Angiogenic Commitment of Mesenchymal Stem Cells

et al. 2017

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“…Implant primary stability is a key factor in achieving osseointegration and is one of the prerequisites for successful immediate/early loading procedures. 1 Primary stability is affected by multiple factors such as bone quality, 2 bone density, 3 bone morphology, 4 implant design, 5 implant surface roughness, 6 preparation of the implant site, [5][6][7][8] crestal bone anchorage, 9 apical anchorage through the cortical floor of the sinus or nasal cavities, 10 lateral cortical anchorage, 11 and implant dimensions. 2,12,13 Optimal implant stability is more difficult to achieve in lowdensity bone, such as that of the posterior maxilla.…”

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confidence: 99%

Insertion Torque of Variable‐Thread Tapered Implants in the Posterior Maxilla: A Clinical Study

Abi-Aad

Daher

Baba

et al. 2018

Journal of Prosthodontics

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Dental Implants With a Platform-Switched Morse Taper Connection and an Osteo Growth Induction Surface

Ghensi

Tonetto

Soldini

et al. 2019

Journal of Craniofacial Surgery

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Aim: The aim of this study was to analyze the clinical outcomes after using an innovative implant system characterized by a modern platform-switched Morse taper connection and an osteo growth induction titanium surface (a particular type of SLA surface). Peri-implant bone loss (PBL) and implant success rate were examined after a 1- to 3-year follow-up. Methods: The study was conducted as a cross-sectional analysis on all patients treated from January 2011 to December 2014 using CLC CONIC implants. Implants were divided into 3 main groups, based on the duration of the follow-up (1 year, 2 years, and 3 years), then subgrouped by diameter, length, and type of prosthetic rehabilitation to compare differences in PBL. X-rays were taken at the time of surgery, at prosthetic loading, at 1 year, and then annually thereafter. Previously-established success criteria were used to assess the implants. Frequency analyses and comparisons between the means (with 95% CI) were conducted for the statistical analysis of the data collected. Results: One hundred twenty patients met inclusion and exclusion criteria, and completed the follow-up, and were thus eligible for the study, with a total of 261 CLC CONIC implants. The mean follow-up was 22.45 months. No implants failed, giving an overall success rate of 100%. The average PBL at 1-year follow-up was 0.047 mm, at 2 years it was 0.128 mm, and at 3 years it was 0.236 mm. Conclusions: The CLC CONIC implant system had a high success rate after 1 to 3 years of follow-up, in line with previous reports in the scientific literature. Combining platform switching with the Morse taper connection enabled stable bone levels to be achieved in the short to medium term.

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Healing at implants placed in bone of different morphology: an experimental study in dogs

Abstract: Similar implant bed preparations performed at premolar and molar sites with different bone morphology, yielding insertion torque values of about 30-35 and 50-55 Ncm, respectively, did not affect osseointegration after 4 months at non-submerged implants.

Cited by 3 publications

References 14 publications

The Biological Properties of OGI Surfaces Positively Act on Osteogenic and Angiogenic Commitment of Mesenchymal Stem Cells

The Biological Properties of OGI Surfaces Positively Act on Osteogenic and Angiogenic Commitment of Mesenchymal Stem Cells

Insertion Torque of Variable‐Thread Tapered Implants in the Posterior Maxilla: A Clinical Study

Dental Implants With a Platform-Switched Morse Taper Connection and an Osteo Growth Induction Surface

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