Healing assessment of osseous defects of periapical lesions associated with failed endodontically treated teeth with use of freeze-dried bone allograft

Saad, A. Yousef; Abdellatief, El-Said M.

doi:10.1016/0030-4220(91)90372-j

Cited by 23 publications

(16 citation statements)

References 22 publications

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“…He was a case of bruxism, and the decreased osseous fill could be attributed to the persistent trauma from occlusion due his clinical condition. The clinical and radiological results were comparable to those of Saad and Abdellatief who used FDBA in similar defects (Saad and Abdellatief 1991). The graft donors in our study ranged in age from 31 to 90 years and included both male and female donors.…”

Section: Discussionsupporting

confidence: 73%

Evaluation of demineralised, freeze-dried, irradiated bone allografts in the treatment of osseous defects in the oral cavity

Gajiwala

Kumar

Chokhani

2006

Cell Tissue Banking

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Demineralised, freeze-dried bone allografts (DFDBA) have been used extensively by dentists in the treatment of periodontal and periapical osseous defects resulting from inflammatory diseases. Their use in India however, is limited by the availability of quality allografts and the high cost of imported alternatives. A study was conducted to assess the osteogenic potential of DFDBA prepared for the first time in India by the Tata Memorial Hospital (TMH) Tissue Bank. The DFDBA was used in the treatment of osseous defects after removal of periapical lesions associated with devitalised teeth in 10 healthy patients. At the 6-month recall visit all the patients showed a remarkable decrease in the grades of mobility, and 9 out of the 10 patients showed radiographic evidence of complete healing of the osseous defects with evidence of normal bony trabaeculae. These findings indicate that the indigenously prepared DFDBA is a cost effective, biocompatible material with osteogenic potential that can be used effectively in treating osseous defects of periapical lesions associated with non vital teeth.

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Section: Discussionsupporting

confidence: 73%

Evaluation of demineralised, freeze-dried, irradiated bone allografts in the treatment of osseous defects in the oral cavity

Gajiwala

Kumar

Chokhani

2006

Cell Tissue Banking

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“…The patients in our study also demonstrated failed endodontic treatment with established periapical pathology, evident on an IOPA radiograph and reported with chronic infection, recurrent pain and pus formation with cervico-facial sinues [11] and is comparable to an earlier study.…”

Section: Discussionsupporting

confidence: 87%

Healing assessment of osseous defects of periapical lesions with use of freeze dried bone allograft

Lingaraj

Kotrashetti

Gupta

2009

J. Maxillofac. Oral Surg.

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Objectives The aim of this study was to save endodontically failed teeth with periapical pathosis by surgery. Elimination of the periapical pathology and to evaluate the clinical and radiological efficiency of freeze dried bone allograft in bony defects. Materials and methods Ten patients were included in this study with established periapical pathology with the need for periapical surgery after failed endodontic therapy. Surgery was decided after the cessation of acute symptoms. Patients on regular medications for known medical complications were excluded from the study. A full thickness flap or modified Leubke-ochsecnbein was raised depending upon the size and location of the lesion. Thorough periapical curettage was performed to remove the pathological tissue surrounding the apices and the root of the tooth. The graft material was mixed with patient's venous blood drawn earlier from a peripheral vein to make it more cohesive. The graft material mixed with blood was then carefully packed with light pressure into the defect. The flap was replaced. All the patients received broad spectrum antibiotics one day before and five days after surgery. The cases were followed up with clinical and radiological examination and were recalled at intervals of 1 month, 3 months and 5 months postoperatively to assess the condition of the periapical area. Results In all the ten cases at the end of 1st month postoperatively a well defined border separating the host bone from the graft material indicating simultaneous resorption of the graft. This resorption continued at 3 months follow up indicating continued graft resorption and also increasing radioopacity, haziness indicating bone regeneration. Eight of the ten patients could be evaluated at the end of fifth month and radiographs showed increase in radioopacity and reduction in size of periapical radiolucency as well as normal trabecular pattern of the bone. Conclusion The results demonstrate successful use of FDBA in the treatment of osseous defects of periapical lesions associated with failed endodontically treated teeth.

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“…Conversely, in a systematic review, fresh-frozen and DFDBA allografts were associated with significant improvements in bone level compared with open flap debridement, although this did not hold true for FDBA (28). When used in periapical defects after root end surgery, one endodontic study demonstrated that FDBA results in histologic periodontal regeneration with no adverse tissue response (29). Similarly, several case reports have demonstrated healing with mature bone and hemopoietic marrow in periapical areas by using DFBA with or without a membrane (30)(31)(32).…”

Section: Allograftsmentioning

confidence: 86%

Periodontal and Endodontic Regeneration

Bashutski

Wang

2009

Journal of Endodontics

139

140

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Healing assessment of osseous defects of periapical lesions associated with failed endodontically treated teeth with use of freeze-dried bone allograft

Cited by 23 publications

References 22 publications

Evaluation of demineralised, freeze-dried, irradiated bone allografts in the treatment of osseous defects in the oral cavity

Evaluation of demineralised, freeze-dried, irradiated bone allografts in the treatment of osseous defects in the oral cavity

Healing assessment of osseous defects of periapical lesions with use of freeze dried bone allograft

Periodontal and Endodontic Regeneration

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