Introduction: Patients with tension-type headache (TTH) are characterized by recurrent pain that can become disabling, accompanied by sensory, motor and neurovascular changes, with a prevalence of between 36 and 78% in adults. Identifying the dietary triggers of headaches has led to defining dietary strategies to prevent this disease since excessive consumption, for example, of fats is widely accepted as unhealthy. Within the essential polyunsaturated fatty acids (PUFA), they have shown that Omega-3 fatty acids (ω-3) have anti-inflammatory and neuroprotective effects of ω-3 fatty acids. In contrast, excessive dietary intake of Omega-6 (ω-6) fatty acids, or an ω-6: ω3 ≥ 5 ratio, typical of Western diets, has been associated with a higher prevalence of headaches.Objectives: The objectives of the present study were to compare dietary fatty acid intake between participants with and without chronic TTH and to investigate the cross-sectional association of dietary fatty acid intake, pain characteristics, and quality of life in patients with chronic TTH.Methods: An observational study was conducted following the Strengthening Statement of the Reporting Initiative on Observational Studies in Epidemiology (STROBE), comparing healthy participants and participants diagnosed with chronic CT, for more than six months according to the Society's Headache Study Group criteria. Spanish of Neurology. For the study we used characteristics of headache episodes, headache impact test and diet analysis as variables.Results: There were no significant differences between the TTH group and the CG in anthropometric and demographic variables. The TTH group reported a significantly higher intake of SFA. Furthermore, significant associations were found between PUFA intake and headache characteristics. However, even though the TTH group reported a significant impact of headaches on their activities of daily living according to the HIT-6 questionnaire, there were no significant correlations between the HIT-6 score and fat intake. Regarding the total daily intake of MUFAs, PUFAs, and ω-6 fatty acids, there were no significant differences between the TTH group and the control group. However, there was a moderate positive correlation between ω-6 fatty acid intake and headache intensity.Conclusion: Chronic tension-type headache patients showed higher intakes of SFA, but similar intakes of MUFAs, PUFAs and ω-6: ω-3 ratio when compared to controls. In addition, Ω-6 fatty acids intake and ω-6: ω-3 ratio were associated with headache episodes.