Headache in children and adolescents after organ transplantation

Uutela, Aki; Qvist, Erik; Holmberg, Christer; Pihko, Helena; Jalanko, Hannu

doi:10.1111/j.1399-3046.2008.00973.x

Cited by 6 publications

(4 citation statements)

References 20 publications

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“…Symptom distress reflects the emotional anguish experienced through developing symptoms (25) and therefore further study of symptoms occurring after transplantation should focus on those that young people find most distressing and burdensome, such as weight gain, difficulty sleeping, painful joints and headaches. Our study confirms previous reports showing headaches are a common problem in young people after transplantation (48). We also showed that the occurrence of headaches had a significant impact on HRQL.…”

Section: The Fact That Psychological Function Is Similarly Low In Asupporting

confidence: 92%

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Study of the Factors Affecting Health-Related Quality of Life in Adolescents After Liver Transplantation

Taylor

Franck

Donaldson

et al. 2009

American Journal of Transplantation

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The aim of the study was to identify factors affecting health-related quality of life (HRQL) in adolescents after liver transplantation. HRQL was measured using the CHQ-CF87 in 55 adolescents, aged 12-18 years. Factors associated with HRQL included allograft morbidity, psychological and family-related variables measured through standardized questionnaires. The domains of the CHQ-CF87 were reduced using factor analysis to give physical, psychological and social domains. Impacting factors were identified through stepwise, multiple regression analysis. Adolescents had significantly lower HRQL in every domain except for role/social-behavior and family cohesion compared to the general population. Adolescents experienced median 18 (range 4-31) symptoms related to immunosuppression, 40(75%) had one or more chronic illnesses related to immunosuppression and 12(22%) had a history of emotional difficulties. Self-esteem and emotional health were similar to the general population but behavior and aspects of family function were lower. Following regression analysis, the factors associated with HRQL were: age at transplant, secondary chronic illness, symptom distress, headaches, history of emotional difficulties, self-esteem and family conflict. These explained 57% of the variance in physical function, 61% of psychological function and 39% of social function. HRQL is significantly reduced in adolescents after transplantation, which could be related to immunosuppression and psychosocial factors.

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Section: The Fact That Psychological Function Is Similarly Low In Asupporting

confidence: 92%

“…We used data from a group of adolescents within the same age range as our sample (44 be proxy measure of other more significant but as yet unmeasured factors such as prolonged absences from school or cognitive developmental effects (47). (48). We also showed that the occurrence of headaches had a significant impact on HRQL.…”

Section: Family-related Variablesmentioning

confidence: 99%

Study of the Factors Affecting Health-Related Quality of Life in Adolescents After Liver Transplantation

Taylor

Franck

Donaldson

et al. 2009

American Journal of Transplantation

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“…Physical factors such as symptoms, functional status, and energy level have been shown to have important effects on perceived QOL (12–15, 24). Physical effects from medications may influence adherence with medical therapy, affect school and social functioning, and create emotional stress (9, 24–26, 28). Despite most children reporting satisfactory general health, physical subscale scores verified that physical symptoms such as fatigue, swelling, thirst, and headache were important concerns for children across the older age cohorts.…”

Section: Discussionmentioning

confidence: 99%

Child and parental perspectives of multidimensional quality of life outcomes after kidney transplantation

Anthony

Hébert

Todd

et al. 2009

Pediatric Transplantation

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Kidney transplantation is an optimal therapy for pediatric patients with end-stage kidney disease. This pilot study sought to examine multidimensional QOL outcomes after kidney transplant using VAQOL and General Health, the PedsQL 4.0, PedsQL End Stage Renal Disease Module, and Impact on Family Module. Sample included 12 adolescents aged 13-18 yr and their parent; three children aged eight to 12 yr and their parent; and six parents of children aged two to seven yr. All were 73 months post transplant. The median age at transplant was 9.3 yr and median time since transplant was 3.2 yr. VAQOL mean was 7.7/10 (child report) and 7.3/10 (parent report); the mean general health was 7.4/10. High levels of fatigue (> or =5/10) were reported in 43%. PedsQL subscale mean values were lower than healthy reference scores. PedsQL Renal Module demonstrated great concern with physical appearance and physical symptoms (thirst and headaches), difficulty with peer and family interaction, and school disruption. Low scores on parental emotional function depict the negative impact of transplant on family functioning. Discordance exists between child and parental reports of QOL. Prospective studies are needed to explore multidimensional QOL to improve long-term outcomes after pediatric kidney transplant.

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“…Headache is a common problem among pediatric solid organ transplantation patients. According to the Finnish national cohort of 177 pediatric patients after kidney, liver, and heart transplantation; headache was found in 46% of the patients 5 . Reversible cerebral vasoconstriction syndrome was originally characterized by severe headache with transient and multiple narrowing of cerebral arteries.…”

Section: Figmentioning

confidence: 99%