Headache due to Systemic Disease

Kahn, Kevin A.

doi:10.1002/9781118414019.ch2

Cited by 3 publications

(1 citation statement)

References 137 publications

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“…The exact mechanism of this headache condition in COVID-19 infection is still unknown, but a hypothesis that can be considered is sensitization of pericranial or intracranial pain-sensitive structures through direct infiltration, release of endotoxins, or immune responses of inflammatory mediators due to the SARS-CoV-2 virus [11,19]. Belvis in his case report mentions several factors that may contribute to this condition, namely cervicogenic factors which cause myofascial pain due to poor posture during quarantine, stress factors due to anxiety about worsening COVID-19, and also causes insomnia due to anxiety.…”

Section: Discussionmentioning

confidence: 99%

Headache Characteristic in Covid-19 Infected Patient: A Systematic Review

Setjaputra,

Steven Christian Susianto,

Abdulloh Machin, MD, PhD, Neurologist

2023

a-jhr

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Introduction: The neurotropism of COVID-19 virus has been addressed in several studies, and headache is one of the most frequent neurologic manifestations of COVID-19, with various results of characteristics and phenotype. In this systematic review, we aimed to characterize the most common phenotype of headache in COVID-19 infected patients. Methods: A systematic literature was conducted through Pubmed, SciElo and Cochrane databases with keywords (headache[Title]) AND (covid-19[Title]), ((neurological) AND (headache) AND (characteristic)) AND (covid-19), ((phenotype) AND (headache)) AND (covid-19). We extracted the study design, demographics of subjects, and characteristics of headache (onset, site, lateralization, quality, intensity, and additional symptoms related to headache). Results: We included 1381 subjects with COVID-19 infection who experienced headache symptoms from eligible 9 studies. The majority of our patients had headaches that occurred with COVID-19 symptoms onset (94.2%), ranging from 1 to 10 days after the first COVID-19 symptoms. The most common headache site was frontal (42.3%), followed by diffuse/ holocranial (40.1%), periorbital/retroorbital (24.2%), and temporal (23.8%), with no lateralization/occurring bilaterally (85.9%), and pain characteristic predominantly pressing and tightening (55.9%), throbbing (25.3%), and stabbing (9.8%). Headache intensity measured by VAS score ranged mild to moderate in most cases with duration mostly 1-24 h. 57% of headache patients were also accompanied by fever symptoms. Additional headache symptoms were also recorded, predominantly anosmia/ageusia, followed by photophobia/phonophobia, and nausea/vomiting. Conclusion: Bilateral, long-lasting, with pressing-tightening characteristic headaches accompanied by fever, were more frequent in COVID-19 infected patients, in conjunction with anosmia/ageusia. These features may help physician to determine the headache related to COVID-19.

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Section: Discussionmentioning

confidence: 99%

Headache Characteristic in Covid-19 Infected Patient: A Systematic Review

Setjaputra,

Steven Christian Susianto,

Abdulloh Machin, MD, PhD, Neurologist

2023

a-jhr

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Akuter Kopfschmerz als Notfallsymptom

Eberhardt¹,

Topka²

2019

Notf.med. up2date

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Headache Incidence and Characteristics in COVID-19 Patients

Sharma¹,

Menon²

2022

Annals of Indian Academy of Neurology

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Background: Headache is one of the commonly reported symptoms of coronavirus disease-2019 (COVID-19) illness. A number of studies have been done so far focusing on headache associated with COVID-19 with variable incidence and characteristics. Material and Methods: This study is a prospective study conducted on 120 patients with confirmed COVID-19 illness. Critically ill and ventilated patients were excluded. Demographic data, COVID illness symptom profile, headache characteristics were documented. Patients were followed up at 2 weeks and 4 weeks. For the statistical analysis, Statistical Package for the Social Sciences (SPSS), version 24.0 was used. Results: 120 COVID-19 positive cases were included in the study with a mean age of 54.59 ± 14.89 years (range 21-84 years) with male-to-female ratio of 3:2. 78.33% (94) of patients had various comorbidities. 43.33% (52) cases were diabetic. The presenting symptoms were fever (65%), cough (53.33%), shortness of breath (35%) and myalgia (31.66%). 26 (21.66%) patients reported headache during the COVID illness. 18 (15%) cases had headache attributed as secondary to COVID-19 illness. Out of them, 12 cases were new onset with no past history of headache and 6 cases had a significant change in previous headache episodes. COVID-19 illness precipitated headache episodes similar to past headache type in 8 cases. Headache was the presenting symptom in 8 (6.66%) patients with COVID-19 being detected in the regular hospital screening protocol. Conclusion: Headache was a common symptom in COVID-19 patients. New onset headaches or change in past headache type in patients in the setting of ongoing pandemic should be screened for COVID-19.

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Headache due to Systemic Disease

Cited by 3 publications

References 137 publications

Headache Characteristic in Covid-19 Infected Patient: A Systematic Review

Headache Characteristic in Covid-19 Infected Patient: A Systematic Review

Akuter Kopfschmerz als Notfallsymptom

Headache Incidence and Characteristics in COVID-19 Patients

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