Head Injury and Defibrination

Vecht, C J; Sibinga, C. Th. Smit

doi:10.1016/s0140-6736(74)91245-8

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1975

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“…A preliminary report has already been published (Vecht and Smit Sibinga, 1974). METHODS The study included 34 head injured patients who were divided into three groups: GROUP I Eight patients who all died within 24 hours after admission because of massive brain injury.…”

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confidence: 99%

Disseminated intravascular coagulation and head injury.

Vecht¹,

Sibinga²,

Minderhoud³

1975

Journal of Neurology, Neurosurgery & Psychiatry

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SYNOPSIS Blood coagulation tests were performed on admission to the hospital and on consecutive days after severe and moderate head injury in 34 patients. Platelet counts and fibrinogen were normal at admission and raised thereafter. The partial thromboplastin time was shortened at admission and lengthened in the following days. Fibrinolytic activity was enhanced at admission. The ethanol gelation test was negative in all patients during the post-traumatic time course. It was concluded that, in the first 24 hours after injury, activated coagulation was present after head injury. In contrast with data of other authors, disseminated intravascular coagulation did not occur in these series.

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confidence: 99%