Head and neck manifestations of myeloma in Nigerians

Owotade, FJ; Ugboko, V.I.; Ajike, SO; Salawu, L; Amusa, Y B; Omole, M.

doi:10.1016/j.ijom.2005.02.007

Cited by 12 publications

(15 citation statements)

References 22 publications

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“…Solitary bone plasmacytomas usually appear in the bones of vertebrae, ribs, pelvis and pectoral girdle while extramedullary plasmacytomas usually appear on the mucosal surfaces e.g. nasal sinuses, oropharynx, larynx etc [5]. In our case, soft tissue swelling was seen between the lower neck to upper sternum area [6].…”

Section: Discussionmentioning

confidence: 58%

Plasmacytoma Located in the Posterior Mandible: A Case Report

Fındık¹

2015

Int J Oral Dent Health

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Section: Discussionmentioning

confidence: 58%

Plasmacytoma Located in the Posterior Mandible: A Case Report

Fındık¹

2015

Int J Oral Dent Health

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“…Sur 30 cas, Owotade et al [8] ont observé des lésions dans l'extrémité céphalique dans 6 cas. Le MM apparait le plus souvent entre 50 et 80 ans, avec un pic dans la soixantaine.…”

Section: Discussionunclassified

“…Selon Kumar et al [22] et Owotade et al [8], les progrès thérapeutiques (chimiothérapie à fortes doses avec éventuel-lement greffe de moelle osseuse, thalidomide, bisphosphonates. .…”

Section: Discussionunclassified

“…Le MM reste toujours associé à un fort taux de mortalité : la survie moyenne varie de 29 mois à 4 ans [8,25]. Au Mexique, le taux de mortalité dû au MM est passé de 28.1 pour 100 000 habitants en 1955 à 57,2 pour 100 000 habitants en 2002 [26].…”

Section: Discussionunclassified

“…Les lésions du MM touchent principalement les vertèbres, le crâne, le bassin, les côtes, l'humérus et le fémur [5][6][7]. Le sex-ratio homme-femme est de 4 :1 [8], avec une incidence importante entre 50 et 80 ans, et un pic dans la 6 ème décade [7]. Le MM comporte trois variétés histopathologiques (plasmocytaire, anaplasique et plasmoblastique) qui ont une valeur pronostique.…”

Section: Douleurs Osseusesunclassified

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Plasmocytome mandibulaire révélateur d’un myélome multiple. Présentation d’un cas

Urbina

Flores

Salvador

et al. 2010

Med Buccale Chir Buccale

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Key words: plasmocytoma / multiple myeloma / oral pathology Abstract -Mandibular plasmocytoma leading to the discovery of a multiple myeloma. Report of a case. Plasmacytoma is considered as the initial presentation of multiple myeloma (MM), a devastating and fatal disease. MM is more frequent in men (male-female ratio = 4:1) and generally occurs between the 5th and the 8th decade, affecting with greater frequency vertebrae, skull, pelvic bones, ribs, humerus and femur. According to the WHO, in 2002, MM was the 17th cause of death by neoplasms in the world. We report a case of a 30-year-old woman, referred to the Maxillofacial surgery pregraduate school of the Faculty of Odontology of national autonomous University (Mexico) for a swelling of her left jaw, with an initial diagnosis of infection, and later histopathologically diagnosed as a plasmacytoma. A complete work-up including blood tests, urine tests and total-body x-rays led to a definitive diagnosis of MM, with a rare histologic profile, considered to be having a poor prognosis. The patient was subjected to chemotherapy but she passed away five months later. This case represents one of those undiagnosed cases of malignant neoplasms, considered first as an unsuspected infective lesion and treated as such with antibiotic therapy. The case also highlights the role that could be played by the dental profession in the early diagnosis of bone cancers, which often have a poor prognosis.Le MM est une néoplasie maligne développée à partir des lymphocytes B, caractérisée par une prolifération de plasmocytes

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