he efficacy of Traumeel® S in terms of evidence-based medicine

Пилипович, А. А.

doi:10.26442/2075-1753_19.2.157-162

Cited by 9 publications

(2 citation statements)

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“…СЕІ є одним із визначальних типових клініко-патогенетичних синдромів формування і тяжкості хронічного панкреатиту (ХП) [1,5]. Перспективний принцип профілактики та корекції СЕІ -застосування методів, здатних не лише зменшувати клінічну симптоматику, а й нормалізовувати вегетативний статус, регулювати гормональний і метаболічний баланс, що притаманно біорегуляційній терапії [6][7][8][9], вегетотропним препаратам на основі гінкго білоба, які, окрім інших позитивних ефектів, володіють протизапальною дією, що також обґрунтовує доцільність їхнього використання [10][11][12][13][14][15].…”

Section: Discussionunclassified

Efficiency of Complex Correction of Endotoxicosis in Chronic Pancreatitis During Renewal Treatment

Zoriana

Liliia

2022

FMEP

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Clinical manifestations and features of endogenous intoxication syndrome (EIS) in severe and critical conditions are described in the literature. EIS is one of the defining typical clinical and pathogenetic syndromes of the formation and severity of chronic pancreatitis (CP). The objective: to analyze the EIS parameters by CP in patients outside of exacerbation and their impact on the quality of patient’s life and the dynamics under the influence of the proposed treatment programs with the inclusion of ginkgo biloba drugs and bioregulatory therapy. Materials and methods. 100 patients with diagnosis of CP who had outpatient treatment took part in the study. The age of the patients ranged from 25 to 73 years old, the average age was 51.0±1.1 years. EIS was determined based on the concentration of medium molecular weight peptides with maximum absorption at the wavelength 254 nm and 280 nm and circulating immune complexes. Patients’ quality of life was assessed using the SF-36 questionnaire. The patients were divided into three 3 groups. The persons in the 1st group (n=34) received generally accepted treatment (GAT) in accordance with the clinical diagnosis and the protocol proposed by the Ministry of Health of Ukraine (Order No. 638 of 09/10/2014), the patients in the 2nd group (n=33) received GAT together with a course of ginkgo biloba (memoplant), the individuals in the 3rd group (n=33) received the GAT with a course of memoplant and bioregulatory therapy (BRT). Results. In the examined patients with CP a decrease in all indicators of the quality of life according to the SF-36 was found, the parameters of the role (33.7±3.4) and emotional (37.0±3.9) functioning scales decreased mostly, the average value of physical health was 51,1±7.2, psychological one – 45.1±3.9. An increase in EIS indicators was determined, which were reliably correlated with indicators of quality of life. In the patients who received GAT and ginkgo biloba the more significant dynamics of EIS regression were established at the levels of the studied indicators, however, their normalization to the control level was observed only in the 3rd group of patients who received an additional course of BRT (p<0.001). Conclusions. The results of the study determined a negative impact of EIS on parameters of quality of life according to the SF-36 in patients with CP, which justifies the necessity for the correction. A more severe EIS according to the levels of the studied indicators was found among people with excessive and reduced body weight (p<0.05), which indicates a more severe course of the inflammatory process. According to the dynamics of EIS the indicators in patients with CP it is possible to claim a higher efficiency of therapy with additional prescription to the generally accepted treatment of ginkgo biloba and a course of bioregulatory therapy.

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Section: Discussionunclassified

Efficiency of Complex Correction of Endotoxicosis in Chronic Pancreatitis During Renewal Treatment

Zoriana

Liliia

2022

FMEP

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“…There are also often cases of self-treatment when patients take various medications (mainly antibiotics, calcium-containing drugs, etc.) without taking into account the indications and individual dosage of the drug [7,8,10,11,16].…”

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confidence: 99%

The Effectiveness of the New Scheme of Complex Treatment of Fractures of the Lower Jaw

Yakubov,

Shomurodov

2023

tajmspr

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The stable growth and prevalence of mandibular fractures in the structure of injuries of the maxillofacial region against the background of an active process of urbanization determines the urgency of improving diagnostic methods, as well as the development of the most effective comprehensive treatment regimens. In this study, the effect of the drug Traumel® S as part of drug therapy on the processes of consolidation of fragments and healing of fractures of the lower jaw was studied. Along with clinical research methods, the effectiveness of the drug was studied by assessing changes in bone density in the fracture zone using radiography and echosteometry.

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Post-Covid Asthenia Syndrome

Khaibullina,

Maksimov

2023

Neurosci Behav Physi

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he efficacy of Traumeel® S in terms of evidence-based medicine

Cited by 9 publications

References 0 publications

Efficiency of Complex Correction of Endotoxicosis in Chronic Pancreatitis During Renewal Treatment

Efficiency of Complex Correction of Endotoxicosis in Chronic Pancreatitis During Renewal Treatment

The Effectiveness of the New Scheme of Complex Treatment of Fractures of the Lower Jaw

Post-Covid Asthenia Syndrome

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