“…21 Facial malformations associated with trisomy 18 include a small head (microcephaly) accompanied by a prominent back portion of the head, low-set, malformed ears, micrognathia, cleft-lip or palate, an upturned nose, narrow eyelid folds, and widely spaced eyes. 22 In one case of trisomy 18 at 27 weeks and 6 days, a small head accompanied by a prominent back portion of the head, low-set ears, a small jaw, an upturned nose, narrow eyelid folds, and widely spaced eyes were identified using HDlive 13 (Figs 11A and B). In two other cases of trisomy 18 (Figs 12 and 13), HDlive showed more detailed features of the fetal face compared to conventional 3D ultrasound.…”