HDL levels modulate the impact of type 2 diabetes susceptibility alleles in older adults
Siobhán O.’ Sullivan,
Cynthia Al Hageh,
Andreas Henschel
et al.
Abstract:Background
Type 2 Diabetes (T2D) is influenced by genetic, environmental, and ageing factors. Ageing pathways exacerbate metabolic diseases. This study aimed to examine both clinical and genetic factors of T2D in older adults.
Methods
A total of 2,909 genotyped patients were enrolled in this study. Genome Wide Association Study was conducted, comparing T2D patients to non-diabetic older adults aged ≥ 60, ≥ 65, or ≥ 70 years, respectively. Binomial … Show more
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