2002
DOI: 10.1016/s0021-9150(01)00651-7
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HDL and arteriosclerosis: beyond reverse cholesterol transport

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Cited by 535 publications
(376 citation statements)
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References 191 publications
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“…That PC can serve as a source of TG was previously shown in rat hepatocytes for which incubation with [ 3 H]oleic acid increased the amount of radiolabeled cellular and secreted TG with a concomitant loss of labeled PC (36). In addition, when cells were prelabeled with 1,2-di [1][2][3][4][5][6][7][8][9][10][11][12][13][14] C]palmitoylphosphatidylcholine, part of the radiolabel was secreted as TG. More recently, we have shown that 50% of LDL-PC that is taken up by mouse hepatocytes is converted into TG (14).…”
Section: Discussionmentioning
confidence: 99%
“…That PC can serve as a source of TG was previously shown in rat hepatocytes for which incubation with [ 3 H]oleic acid increased the amount of radiolabeled cellular and secreted TG with a concomitant loss of labeled PC (36). In addition, when cells were prelabeled with 1,2-di [1][2][3][4][5][6][7][8][9][10][11][12][13][14] C]palmitoylphosphatidylcholine, part of the radiolabel was secreted as TG. More recently, we have shown that 50% of LDL-PC that is taken up by mouse hepatocytes is converted into TG (14).…”
Section: Discussionmentioning
confidence: 99%
“…25 HDL can also reverse endothelial dysfunction, inhibit LDL oxidation, stimulate endothelial cell proliferation and prostacyclin generation. 26 Lowered HDL level diminishes these benefits and increases the risk of thrombosis. On the contrary Ullrich, Aurbach and Drobik 22 indicated that both hyperlipidaemia and atherogenic risk factors are not major pathological importance in SSNHL.…”
Section: Discussionmentioning
confidence: 99%
“…Lipoproteins are object of extensive research for last 40 years due to their active role in atherogenesis (Nofer et al 2002;Barter et al 2003). The spherical particles consist of polar lipid monolayer which encapsulates apolar lipids (Gotto 1987).…”
Section: Introductionmentioning
confidence: 99%