Abstract:Background: Although a role of the human cytomegalovirus (HCMV) in atherosclerosis and restenosis is probable, clinical studies are not conclusive. The present study investigates in a threedimensional (3D) human coronary transfilter co-culture model the effect of cell-free and cell-associated HCMV-infection. Methods: Human coronary endothelial cells (HCAEC) and HCMSMC were seeded on both sides of a polycarbonate filter membrane. HCMV-infection was carried out by HCMV-infected MO. As controls MO-attack without … Show more
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