Has Unstable Angina Become a Vestigial of the Past in Clinical Trial Primary Endpoints?

Bhatt, Deepak L.

doi:10.1159/000524700

Cited by 1 publication

(1 citation statement)

References 16 publications

(18 reference statements)

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“…Indeed, some studies have indicated that exercise can improve endothelial cell function[ 26 ]. Rehabilitation exercise training accelerates blood circulation and plaque dissolution, increases intravascular blood flow and oxygen supply to the heart, and achieves oxygen saturation, thus ensuring the structural and functional stability of cardiac function[ 27 ]. Rehabilitation training also reduces the amount of fat that accumulates in the body and enhances the physical fitness of elderly patients[ 28 ].…”

Section: Discussionmentioning

confidence: 99%

Effects of systematic cardiac rehabilitation training in elderly patients with unstable angina following cardiac stent implantation

Yan,

Yang,

Chen

et al. 2024

World J Clin Cases

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BACKGROUND Coronary stent implantation is usually used to treat unstable angina to alleviate stenosis or occlusion, promoting blood flow restoration and alleviating symptoms such as myocardial ischemia. And postoperative cardiac rehabilitation is essential for enhancing recovery and prognosis. Nevertheless, conventional rehabilitation lacks specificity, particularly for elderly patients with multiple comorbidities and poor compliance, rendering it less effective. AIM To investigate the effects of systematic cardiac rehabilitation training in elderly patients with unstable angina following coronary stenting intervention. METHODS A retrospective enrollment was conducted comprising fifty-four elderly patients with unstable angina pectoris who underwent systematic cardiac rehabilitation training after receiving coronary intervention as the rehabilitation group, while fifty-three elderly patients who received basic nursing and rehabilitation guidance measures after coronary intervention were assigned to the control group. Differences in Seattle Angina Questionnaire scores, survival quality (SF-36) scores, cardiopulmonary exercise function assessment index, echocardiographic cardiac function index, and adverse cardiovascular events were compared between the two groups. RESULTS After intervention, the rehabilitation group observed greater VO2 Max, maximum metabolic equivalent, eft ventricular ejection fraction, left ventricular end-diastolic diameter and smaller left ventricular end-systolic diameter. And the rehabilitation group observed greater scores of physical activity limitation, stable angina pectoris, treatment satisfaction, and SF-36 score. The incidence of adverse cardiovascular events in the two groups, showed no significant difference. CONCLUSION Systematic cardiac rehabilitation following coronary stenting in elderly patients with unstable angina pectoris can enhance cardiac function recovery, consequently enhancing both quality of life and cardiopulmonary exercise tolerance.

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Section: Discussionmentioning

confidence: 99%