Harnessing the power of polyol-based polyesters for biomedical innovations: synthesis, properties, and biodegradation

Abstract

Polyesters based on polyols have emerged as promising biomaterials for various biomedical applications, such as tissue engineering, drug delivery systems, and regenerative medicine, due to their biocompatibility, biodegradability, and versatile...

Effects of blending poly (polyol sebacate) and poly (polyol adipate) bioelastomers for soft tissue engineering in biomedical applications

“…The findings of this research, in comparison to other articles, demonstrate that, unlike polymers with a single degradation rate, it is achievable to attain the adjusted degradation rate through blending while maintaining suitable properties. 5,9,17 In other studies, it has been observed that adjusting the crosslink density, using different monomers, and blending with incompatible polymers are methods used to control the degradation rate. However, these modifications lead to reduced biocompatibility and affect the physical and mechanical properties.…”

“…These features make them well-suited for tissue engineering and drug delivery purposes. [4][5][6][7] However, it is important to note that PPS bioelastomers are not ideal for long-term applications and may require modifications to their properties for tissue engineering purposes. [8][9][10][11] PPA bioelastomers offer properties similar to PPS polymers for tissue engineering applications, but these polymers have certain limitations too that must be considered.…”

“…These bioelastomers are synthesized from endogenous monomers compatible with human metabolism, resulting in reduced toxicity of the degradation products. 5,9,14,15 These polymers are prepared using monomers that are biocompatible and do not release any toxic substances when they are degraded. 4,[19][20][21][22] These polymers offer another benefit in terms of their synthesis method.…”

“…The esterification process used for these bioelastomers can be carried out without catalysts, initiators, and accelerators that have multiple advantages, including reducing chemical pollution and enhancing the biocompatibility of the polymers. 1,5,6,9 However, the modification of degradation and the physical and mechanical characteristics of bioelastomers for soft tissue engineering has posed challenges. 8,9,11,23 Wang et al discovered that poly (glycerol sebacate) shows linear behavior and possesses various advantageous properties for intracorporeal implants.…”

Soybean oil‐based nanocomposites for dye adsorption: AESO‐chitosan‐graphene oxide synergy in water treatment

“…In addition to their sustainability, plant oils are both cost‐effective and widely available on a global scale. Over the past decade, the utilization of plant oils as eco‐friendly raw materials for the synthesis of biopolymers has garnered considerable attention within the scientific community 29 . Among the plant oil family, soybean oil and its derivatives stand out as some of the most accessible and well‐regarded members, with recent research exploring their applications in areas such as bioinks, 30 green composites, 31 bio‐based coatings, 32 and autonomous self‐healing materials 33 .…”