Abstract:Diseases involving unregulated cell reproduction, (i.e. cancer) can be inhibited through acetyl coenzyme‐A carboxylase (ACC) manipulation, preventing the lipid production that is imperative for cell survival. ACC catalyzes the first step in the fatty acid biosynthesis. ACC contains two dimers, biotin carboxylase (BC) and carboxyltransferase (CT), and a monomer, biotin carboxyl carrier protein (BCCP). Though BC, CT, and BCCP are separate proteins in prokaryotes, they are linked in a single unit within a eukaryo… Show more
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