Abstract:Quantitative characterization of pharmacokinetics (PK) and pharmacodynamics (PD) of drugs is an essential component in pharmacology/toxicology education as well as drug discovery/development. PK determines the relationship between the dose of the administered drug and the concentration measured in the body, whereas PD characterizes the extent of pharmacological effect induced by drug concentrations. Simulation and modeling of such properties is a powerful tool to predict drug's efficacy and toxicity with the l… Show more
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