Hands and Wrists of the Diabetic Child

Bogan, Isabel K.

doi:10.1001/archpedi.1940.01990150123007

Cited by 10 publications

(4 citation statements)

References 5 publications

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“…Although therefore we have tended to exaggerate the BA delay of our patients the conclusions of the study would not be affected by the bone age standards employed since all patients were measured on the same standards and matched for bone age range. Delay of skeletal maturity in diabetic children has been noted previously (Bogan, 1940;Wagner et al, 1942;Craig, 1970;Evans et al, 1972) and appeared as in the present study to be related to the duration of diabetes. However, we were unable to establish a relationship in our patients between serum DHAS concentrations and either BA delay or duration of diabetes.…”

Section: Testicular Colume (' T V ) (Fig 3 )supporting

confidence: 87%

Dissociation of Adrenarche and Gonadarche in Diabetes Mellitus

Cohen

Paterson

Wallace

et al. 1984

Clinical Endocrinology

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Serum concentrations of testosterone and dehydroepiandrosterone sulphate (DHAS) have been measured in 10 stable insulin-dependent diabetic (IDD) males (chronological age (CA) range 13.0-17.5 years). Their results have been compared with those of a control population of 69 non-diabetic males who presented with mild constitutional growth delay and whose skeletal maturity and pubertal development were similar to the diabetic subjects. Within bone ages (BA) 11.0-14.5 years no significant difference was observed between the serum testosterone concentrations of the diabetic patients and controls: diabetic males, 8.2 (0.3-25) nmol/l (median and range); controls, 7.0 (less than 0.3-23) nmol/l. In contrast, within BA 11.0-14.5 years, the diabetic males had significantly lower serum DHAS concentrations: diabetic males, 1.1 (0.7-4.2) mumol/l; controls, 3.7 (0.7-5.6) mumol/l (P less than 0.001). The serum DHAS concentrations of the diabetic males were also significantly lower than the controls when matched separately for pubic hair and genital development, testicular volume and serum testosterone, (in each comparison P less than 0.02). Serum DHAS concentrations of the diabetic males did not correlate significantly with CA, BA, BA delay (CA-BA), age of onset of diabetes, duration of diabetes, or glycosylated haemoglobin (GHb), but significant correlation was observed between BA delay and duration of diabetes, r = 0.65, P less than 0.05. We conclude that gonadarche appears to proceed despite delayed adrenarche in IDD males. This study presents further evidence in favour of adrenarche and gonadarche being independent physiological events. The causes and clinical significance of low serum DHAS concentrations in adolescent diabetic males remain to be established.

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Section: Testicular Colume (' T V ) (Fig 3 )supporting

confidence: 87%

Dissociation of Adrenarche and Gonadarche in Diabetes Mellitus

Cohen

Paterson

Wallace

et al. 1984

Clinical Endocrinology

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“…Wagner et al (1942) reported general retardation of bone age in children with diabetes. Bogan (1940) found retardation in 600°of males and 51 0o of females. She also noted that the longer the duration of diabetes the greater the tendency to retardation.…”

Section: Resultsmentioning

confidence: 93%

Growth and Bone Age of Juvenile Diabetics

Evans¹,

Robinson²,

Lister³

1972

Archives of Disease in Childhood

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“…Juvenile diabetes mellitus has been shown to affect the general growth of patients with earlier onset of the disease, especially onset before or around the circumpubertal growth spurts. 13,14,18 Many investigators have reported that this growth impairment in JD patients is more significant in boys than in girls. 19,20 Males comprised the selected sample in order to obtain more representative data regarding skeletal maturation from hand-wrist radiographs.…”

Section: Discussionmentioning

confidence: 99%

“…11,12 Hand-wrist radiographs have been studied in juvenile diabetics. 13 There is delayed appearance or delayed development of a center of ossification, usually of a carpal bone. These defects occur twice as frequently in boys than in girls, and the total incidence of juvenile diabetics with anomalies and developmental defects is 24.3%.…”

Section: Introductionmentioning

confidence: 99%

Study of craniofacial morphology in children with juvenile diabetes

Mushayt¹,

Nwaiser²

2005

Egyptian Orthodontic Journal

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Previous studies have shown that patients with JuvenileDiabetes have growth retardation. Also, previous researches have also that there is relationship between the general body growth and craniofacial maturation. The purpose of this study was to evaluate the craniofacial morphology and to relate it to the degree of diabetes in children with Juvenile Diabetes. Thirty growing children (age range 14-16 year) who had Juvenile Diabetes (JD) for 3-5 years and that were been treated by daily administration with insulin were studied. Another healthy thirty children with no familial history of any endocrinal disorders or Juvenile Diabetes and who attend the orthodontic /Pedodontic clinics of KAAU seeking orthodontic treatment were chosen. Lateral cephalomteric radiographs were taken for each patient after consenting patients to participate in this study. All cephalometric radiographs were corrected for magnification distortion and analyzed to evaluate their craniofacial growth status. The results showed that JD patients are underdeveloped in most of the craniofacial skeletal and soft tissue parameters when compared with the control group.

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Hands and Wrists of the Diabetic Child

Cited by 10 publications

References 5 publications

Dissociation of Adrenarche and Gonadarche in Diabetes Mellitus

Dissociation of Adrenarche and Gonadarche in Diabetes Mellitus

Growth and Bone Age of Juvenile Diabetics

Study of craniofacial morphology in children with juvenile diabetes

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