Handling and Pathology Reporting of Renal Tumor Specimens

Histopathology of surgically treated renal tumours in young adults: a developing country perspective

“…Gross handling of nephrectomy specimens was done according to the standard protocol for examining nephrectomy specimens (Rosai 2004;Algaba et al 2004;Fleming and GriYths 2005). Representative tissue blocks were taken and processed for paraYn embedding, hematoxylin and eosin (H and E) stained and examined by two experienced pathologists with special interest in renal, transplant and urologic pathology (JIK and MM).…”

IMA901: A multi-peptide cancer vaccine for treatment of renal cell cancer

“…19 Based on the findings of routinely conducted histological assessments, patients are grouped into 5 major histologic subtypes, which differ in prognosis and response to anti-tumor therapy. 20,21 Clear cell renal cell carcinoma (ccRCC) is the most prevalent histologic subtype being assigned to 70-80% of all RCC patients. The prognosis of patients with ccRCCs is less favorable compared with papillary (chromophile) RCCs accounting for 10-15% of RCCs and chromophobe RCCs being responsible for 3-5% of RCC cases.…”

Intraoperative and surgical specimen (ex vivo) ultrasound in the assessment of margins at partial nephrectomy

“…However, speedy assessment of specimen resection margin may justify the additional few minutes of warm ischaemia, especially in the selected group. Finally, manipulation and cutting through the specimen before inking, which can alter microscopic final pathological results, can be avoided using ex vivo US [18].…”