Handheld dermatoscopy as an easy-to-use capillaroscopic instrument in rheumatoid arthritis: a cross-sectional study

Elmas, Ömer Faruk; Okçu, Mehmet; Demirbaş, Abdullah; Akdeniz, Necmettın

doi:10.3906/sag-2006-6

Cited by 6 publications

(5 citation statements)

References 23 publications

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“…The capillaroscopic results of periungual folds obtained with the dermatoscope are comparable to those described with other instruments such as Video-Capillaroscopy [9][10][11][12][13] . In addition, it has been observed that periungual telangiectasias and cuticle dystrophy are associated with the level of cutaneous activity in DM patients 12,13 .…”

Section: Introductionsupporting

confidence: 77%

Trichoscopic, oral and periungual fold findings as activity and damage markers in Dermatomyositis patients and their correlation with myositis antibodies

Salgueiro

Poblete

Robles-Silva

et al. 2022

Preprint

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There is little clarity about the clinical manifestations of dermatomyositis (DM) in the periungual folds, scalp, and oral cavity and their association with disease activity and damage. The objective of this study was to compare the prevalence of trichoscopic, oral, and periungual changes between DM and healthy patients and assess their possible association with disease activity and damage. We conducted an observational, transversal, and analytical study between 2020 and 2021. Forty DM patients were matched by sex and age with 40 healthy individuals. On the same day, all patients had a clinical evaluation of the hands, periungual folds, scalp, and oral cavity. Photographs of these areas and peripheral venous blood tests, including myositis-associated (MAAs) and myositis-specific antibodies (MSAs), were taken. Two dermatologists blinded to their diagnosis, damage, and activity levels registered the lesions. The disease activity and damage were evaluated using the Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI). The presence of mechanic’s hands, Gottron’s sign, and Gottron’s papules in hands; capillary dilation, capillary tortuosity, cuticular hemorrhage, avascular areas, and cuticular hyperkeratosis in periungual folds; thick tortuous capillaries in scalp; gingival telangiectasias in the oral cavity; and positive MSAs associated with severe cutaneous involvement in DM patients (Anti-TIF1g, Anti-MDA5, Anti-SAE1/2) were associated with a higher CDASI activity score. The presence of MSAs associated with intense muscle involvement in DM patients (Anti-Mi2a, Anti-Mi2b, Anti-NPX2, and Anti-SAE1/2) was related to a lower CDASI activity score. Gottron’s sign and Gottron’s papules in hands; capillary dilation, capillary tortuosity, cuticular hemorrhage, avascular areas, and cuticular hyperkeratosis in periungual folds; basal erythema in scalp; and gingival telangiectasias in the oral cavity were associated with a higher CDASI damage score. There are trichoscopic, oral and periungual fold findings, and some myositis-specific antibodies that correlate with disease activity and damage in DM patients.

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Section: Introductionsupporting

confidence: 77%

Trichoscopic, oral and periungual fold findings as activity and damage markers in Dermatomyositis patients and their correlation with myositis antibodies

Salgueiro

Poblete

Robles-Silva

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…The capillaroscopic results of periungual folds obtained with the dermatoscope are comparable to those described with other instruments such as videocapillaroscopy [9][10][11][12][13]. In addition, it has been observed that periungual telangiectasias and cuticle dystrophy are associated with the level of cutaneous activity in DM patients [12,13].…”

Section: Introductionsupporting

confidence: 72%

Trichoscopic, oral, and periungual fold findings as activity and damage markers in dermatomyositis patients and their correlation with myositis antibodies

et al. 2023

View full text Add to dashboard Cite

There is little clarity about the clinical manifestations of dermatomyositis (DM) in the periungual folds, scalp, and oral cavity and their association with disease activity and damage. The objective of this study was to compare the prevalence of trichoscopic, oral, and periungual changes between DM and healthy patients and assess their possible association with disease activity and damage. We conducted an observational, transversal, and analytical study between 2020 and 2021. Forty DM patients were matched by sex and age with 40 healthy individuals. On the same day, all patients had a clinical evaluation of the hands, periungual folds, scalp, and oral cavity. Photographs of these areas and peripheral venous blood tests, including myositis-associated (MAAs) and myositis-specific antibodies (MSAs), were taken. Two dermatologists blinded to their diagnosis, damage, and activity levels registered the lesions. The disease activity and damage were evaluated using the Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI). The presence of mechanic’s hands, Gottron’s sign, and Gottron’s papules in hands; capillary dilation, capillary tortuosity, cuticular hemorrhage, avascular areas, and cuticular hyperkeratosis in periungual folds; thick tortuous capillaries in scalp; gingival telangiectasias in the oral cavity; and positive MSAs associated with severe cutaneous involvement in DM patients (Anti-TIF1g, Anti-MDA5, Anti-SAE1/2) were associated with a higher CDASI activity score. The presence of MSAs associated with intense muscle involvement in DM patients (Anti-Mi2a, Anti-Mi2b, Anti-NPX2, and Anti-SAE1/2) was related to a lower CDASI activity score. Gottron’s sign and Gottron’s papules in hands; capillary dilation, capillary tortuosity, cuticular hemorrhage, avascular areas, and cuticular hyperkeratosis in periungual folds; basal erythema in scalp; and gingival telangiectasias in the oral cavity were associated with a higher CDASI damage score. There are trichoscopic, oral and periungual fold findings and some myositis-specific antibodies that correlate with disease activity and damage in DM patients. Supplementary Information The online version contains supplementary material available at 10.1007/s00403-023-02554-0.

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“…This evaluation can be performed using videocapillaroscope, USB microscope as well as dermoscope. The last device is available in the office of almost all dermatologists and it proved to be valuable tool for detection of microvascular abnormalities in CTDs 8,9 or evaluation of microvasculopathy in patients with SSc 10 . Dermoscopic evaluation of capillaries in nailfolds showed previously good inter‐ and intraobserver reliability to be promoted as alternative tool for widefield NFC 11–13,3 .…”

Section: Discussionmentioning

confidence: 99%

Role of short courses on nailfold capillaroscopy in obtaining abilities for the identification of microvasculopathy in patients with Raynaud's phenomenon

Miziołek

Pieczyrak

Polak

et al. 2022

Skin Research and Technology

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Introduction An early distinction between “normal” and “abnormal” capillaroscopic pattern during the first visit to a dermatologist has a crucial significance for a diagnostic management of Raynaud's phenomenon (RP). There exists a question about the level of expertise sufficient to evaluate the microcirculation. Aim To evaluate the utility of short courses on NFC among dermatologists and medical students in obtaining sufficient abilities for the identification of microvasculopathy in patients with RP using videocapillaroscope and handheld dermoscope. Methods Both groups participated in 1‐h course on NFC. Before the course, participants were asked to classify 20 videocapillaroscopic and 10 dermoscopic capillaroscopic pictures into “normal” or “abnormal” pattern. Each picture was displayed on a separate slide MS PowerPoint for 10 s. The evaluation was repeated soon after the course. Results A total of 36 dermatologists and 49 medical students were enrolled. The rate of properly classified dermoscopic and videodermoscopic pictures increased after the course in both groups, but students improved the accuracy of classification on dermoscopic pictures to the greater extent than dermatologists. The rate of correctly recognized pictures with “abnormal” pattern was significantly greater than ones with “normal” pattern at the baseline and after the course, independently of imagining tool. Conclusions Short courses on NFC may improve the classification of capillaroscopic images, even in medical staff with no previous experience in NFC. The recognition of capillaroscopic abnormalities seems to be easier than obtaining the confidence that evaluated picture has “normal pattern.”

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Handheld dermatoscopy as an easy-to-use capillaroscopic instrument in rheumatoid arthritis: a cross-sectional study

Cited by 6 publications

References 23 publications

Trichoscopic, oral and periungual fold findings as activity and damage markers in Dermatomyositis patients and their correlation with myositis antibodies

Trichoscopic, oral and periungual fold findings as activity and damage markers in Dermatomyositis patients and their correlation with myositis antibodies

Trichoscopic, oral, and periungual fold findings as activity and damage markers in dermatomyositis patients and their correlation with myositis antibodies

Role of short courses on nailfold capillaroscopy in obtaining abilities for the identification of microvasculopathy in patients with Raynaud's phenomenon

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