Handgrip strength measurement protocols for all-cause and cause-specific mortality outcomes in more than 3 million participants: A systematic review and meta-regression analysis

Cruz, Borja del Pozo; Gallardo-Gómez, Daniel; Calatayud, Joaquín; Cruz‐Montecinos, Carlos; López-Gil, José Francisco; López‐Bueno, Rubén

doi:10.1016/j.clnu.2022.09.006

Cited by 7 publications

(6 citation statements)

References 77 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results from our study are in line with those from the earlier research [ 12 , 17 , 42 – 44 ] indicative of associations of lower GS with higher all-cause and CVD mortality risk. In a prospective population-based study, with the age range of participants 40–69 years, muscle weakness (defined as GS < 26 kg for men and < 16 kg for women) was associated with a higher hazard for all health outcomes, except colon cancer in women and prostate cancer and lung cancer in both men and women [ 45 ].…”

Section: Discussionsupporting

confidence: 93%

“…Hand-grip dynamometry, the measurement of GS has been widely adopted as a singular indicator of overall strength [ 11 ]. Studies have confirmed the value of GS as a predictor of physical functioning, morbidity, and disability in old age, and mortality, as well as an indicator of health outcomes in healthcare, such as hospital length of stay [ 8 , 12 , 13 ]. An inverse association between muscle strength and cardiovascular health has been reported, and poor cardiovascular outcomes have been demonstrated in initially healthy individuals of all age groups, and in those with existing disease [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

“…Recent data from a systematic review and meta-regression analysis concluded that protocols used to assess GS in mortality studies were incomplete and highly heterogeneous. GS values were found to be higher when studies controlled fewer GS measurement protocol variables [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Longitudinal association of grip strength with cardiovascular and all-cause mortality in older urban Lithuanian population

Sileikiene,

Tamosiunas,

Luksiene

et al. 2024

BMC Public Health

View full text Add to dashboard Cite

Background Ageing populations experience greater risks associated with health and survival. It increases the relevance of identifying variables associated with mortality. Grip strength (GS) has been identified as an important biomarker for all cause and cardiovascular mortality, however, its prognostic value has not been studied in Lithuania. The aim of the present study is to evaluate the relationship of GS to vital status in a representative sample of the Lithuanian 45–72-year-old urban population during the period of 12 years of follow-up and to explore associations of GS with all-cause mortality and mortality from cardiovascular diseases (CVD). Methods Within the framework of the international study Health, Alcohol and Psychosocial Factors in Eastern Europe (HAPIEE) 7,115 men and women 45–72 years of age were examined in the baseline survey (2006 to 2008). Data from the Official Lithuanian Mortality Register were used to evaluate CVD and all-cause mortality from follow-up till 2020. Cox proportional hazards regression was used, and four models for all-cause and CVD mortality were assessed. Results The mean GS was significantly higher among survivors’ men and women as compared to individuals deceased from CVD and other causes of death. In survivor men and women groups, minimal values of GS in all terciles were higher as compared to all three deceased groups. In both men and women groups, the lowest GS (1st tercile) was associated with a significantly higher risk of all-cause and CVD mortality as compared to the highest levels of GS (3rd tercile) in three Cox regression models. In both men and women were found to have a 1.34- and 1.35-fold higher risk of all-cause mortality, respectively, at lower GS, but no significant difference in the risk of CVD mortality. When GS was treated in all models as decrement per 1 kg and decrement per 1 SD, in both men and women, the risk of all-cause mortality significantly increased with decreasing of GS. Conclusions The mean GS was significantly higher among survivors’ men and women as compared to deceased from CVD and other causes of death. Risk of all-cause mortality significantly increased with decreasing of GS.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Longitudinal association of grip strength with cardiovascular and all-cause mortality in older urban Lithuanian population

Sileikiene,

Tamosiunas,

Luksiene

et al. 2024

BMC Public Health

View full text Add to dashboard Cite

show abstract

“…However, it is important to note that the effectiveness of physical functional tests is much more erratic than that of radiological studies, and that there is a considerable influence on patient psychology, which has led to conflicting results in many studies, most likely due to limited sample sizes, lax implementation of testing criteria, or excessive heterogeneity of patient populations. [20,21] This study also lacked sufficient longitudinal data, and some scholars have shown that changes in skeletal muscle before and after treatment are also useful to guide the optimization of the surgical cohort, and to evaluate the benefits of treatment and timely resistance training. We also did not search for sufficient studies on the dynamic assessment of body composition in HCC patients receiving TACE.…”

Section: Discussionmentioning

confidence: 99%

Prognostic value of sarcopenic visceral obesity in hepatocellular carcinoma treated with TACE

Hou

Chen

2023

Medicine

View full text Add to dashboard Cite

Although Transartial chemoembolization (TACE) is one of the recommended treatments for hepatocellular carcinoma (HCC), there is always a dispute on the selection of the best beneficiary for treatment. We studied the prognostic value of nutritional markers, obesity, visceral obesity and sarcopenia on survival outcomes under single and different combinations. In a retrospective cohort of 235 patients with HCC at different stages, more accurate comprehensive prognostic factors were obtained by combining and comparing the multifactor hazard ratios (HR) of various parameters, including skeletal muscle index (SMI) and visceral fat index (VFI) obtained by computer tomography, laboratory index albumin-to-globulin (A/G) ratio, anthropometric body mass index (BMI) and other parameters. The study cohort was dominated by men (73.6%), with a median age of 54 years. According to the survival outcome of HCC patients, we obtained the ideal sex cutoff value of VFI: ≥40.54 cm2/m2 for males (the receiver operating characteristic curve [ROC] = 0.764, P < .001) and ≥ 43.19 cm2/m2 for females (ROC = 0.718, P < .05). According to the results of multifactor analysis, sarcopenic visceral obesity (HR = 8.35, 95% confidence intervals [CI] = [4.96, 14.05], P < .001) is more effective than any single or combined prognosis assessment, including sarcopenic dystrophy (HR = 2.70, 95% CI = [1.85, 3.95], P < .001), sarcopenic obesity (HR = 5.23, 95% CI = [3.41, 8.02], P < .001), sarcopenia (HR = 5.74, 95% CI = [3.61, 9.11], P < .001) and visceral obesity (HR = 3.44, 95% CI = [2.24, 5.27], P < .001). Sarcopenic visceral obesity, defined by SMI and VFI, is a more objective and accurate prognostic indicator of HCC.

show abstract

“…These joints were chosen because they are the most commonly affected joints in PWH 1 . Additionally, handgrip strength was measured as an indicator of total strength using a hand dynamometer with an adjustable grip (TKK 5101 Grip D; Takey, Tokio, Japan) following previous recommendations 27 . A total of three repetitions were completed with the dominant limb and the mean was used in the analysis.…”

Section: Methodsmentioning

confidence: 99%

Benefits of physical activity self‐monitoring in patients with haemophilia: a prospective study with one‐year follow‐up

Pérez‐Alenda,

Carrasco,

Querol‐Fuentes

et al. 2024

Haemophilia

View full text Add to dashboard Cite

IntroductionActivity wristbands have been shown to be effective in relation to self‐monitoring activity levels and increasing exercise adherence. However, previous reports have been based on short‐term follow‐ups in people with haemophilia (PWH).Aim(1) To evaluate compliance with physical activity (PA) recommendations in PWH during a 1‐year follow‐up period using activity wristbands to record daily steps and intensity; (2) To determine the effect of PA self‐monitoring on clinical outcomes.MethodsA prospective observational study was conducted in 27 adults with severe haemophilia undergoing prophylactic treatment. The Fitbit Charge HR was used to track daily PA for an entire year. The participants were encouraged to try to reach a goal of 10,000 steps/day and to track their progress. The pre‐ and post‐evaluation included quality of life (A36 Hemophilia‐QoL Questionnaire), joint health (Haemophilia Joint Health Score), functionality (Timed Up and Go test), and muscle strength.ResultsA total of 323.63 (95%CI: 194–364) valid days (i.e., > 2000 steps) were recorded. The annual average number of steps per day taken by participants was 10,379. Sixteen (59%) PWH reached 10,000 steps/day at baseline and 17 (63%) at 1 year follow‐up, with no significant differences (x2 = .33; p = .56). A statistically significant improvement was observed in daily moderate activity time (p = .012) and in the ‘physical health’ quality of life subscale (mean difference: 2.15 points; 95%CI: .64‐3.65; p = .007).ConclusionOur results suggest that patients with severe haemophilia who self‐managed their PA can improve their long‐term quality of life in the domain of physical health and also the daily time spent in moderate‐intensity PA.

show abstract

Handgrip strength measurement protocols for all-cause and cause-specific mortality outcomes in more than 3 million participants: A systematic review and meta-regression analysis

Cited by 7 publications

References 77 publications

Longitudinal association of grip strength with cardiovascular and all-cause mortality in older urban Lithuanian population

Longitudinal association of grip strength with cardiovascular and all-cause mortality in older urban Lithuanian population

Prognostic value of sarcopenic visceral obesity in hepatocellular carcinoma treated with TACE

Benefits of physical activity self‐monitoring in patients with haemophilia: a prospective study with one‐year follow‐up

Contact Info

Product

Resources

About