Handcrafted Vacuum‐Assisted Device for Skin Ulcers Treatment Versus Traditional Therapy, Randomized Controlled Trial

González, Isaías Vicente Lugo; Andrade, Luis Angel Medina; Baez, Maria Valeria Jimenez; Flores, Brenda Ruiz; Ferretiz, Maria de los Angeles Martinez; Woolf, Stephanny Vanestty; López, Israel; Sandoval-Jurado, Luis; Pat-Espadas, Fany Guadalupe; Cruz, Alan Alejandro Reyes; Delgado, Arsenio Torres

doi:10.1007/s00268-016-3782-9

Cited by 10 publications

(7 citation statements)

References 42 publications

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“…Based on the results of the literature search, several articles discussed NPWT. The first, second, and third articles focused on postoperative foot patients in the presence of surgical site infection (SSI) (Benrashid et al, 2020 ; Costa et al, 2020 ; Deborre et al, 2021 ), while the fourth, fifth, and sixth discussed NPWT for split skin grafts of diabetic foot ulcers on the wound healing process with a decrease in infection in vivo and in vitro (Gonzalez et al, 2017 ; Maduba et al, 2020 ; Seidel et al, 2020 ). Furthermore, the seventh article examined infection control in postoperative mastectomy patients (De Rooij et al, 2021 ), while the eighth reported vascular foot wound healing (Chiang et al, 2017 ).…”

Section: Resultsmentioning

confidence: 99%

“…The eighth article used a similar design with a total sample of n = 144 in diabetic ulcer patients with venous and arterial insufficiency for ten days, divided into the intervention ( n = 72) and the control group ( n = 72). The measuring instrument was wound assessment (Gonzalez et al, 2017 ). Furthermore, the ninth article used an RCT design on a total sample of n = 72 with post-infected complex injuries and divided into an intervention ( n = 36) and a control group ( n = 36).…”

Section: Resultsmentioning

confidence: 99%

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Effectiveness of negative pressure wound therapy on chronic wound healing: A systematic review and meta-analysis

Burhan¹,

Khusein²,

Sebayang³

2022

Belitung Nurs J

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Background: Negative Pressure Wound Therapy (NPWT) is considered an effective treatment in facilitating the healing of chronic wounds. However, its effect remains inconsistent, which allows for further investigation. Objective: This study aimed to assess the effectiveness of the NPWT program in improving the management of chronic wound healing. Design: Systematic review and meta-analysis was used. Data Sources: The search strategy ranged from 2016 to 2021 in PubMed, CINAHL, ProQuest, and ScienceDirect. Review Methods: Risk of bias was done based on the Risk of Bias 2.0 guideline using RevMan 5.4.1, and meta-analysis was done using Jeffreys’s Amazing Statistics Program (JASP) software version 0.16.3. Critical appraisal of the included articles was done according to Joanna Briggs Institute’s (JBI) appraisal checklist. Results: A total of 15 articles were included, with 3,599 patients with chronic wounds. There was no publication bias in this study seen from the results of the Egger’s test value of 0.447 (p >0.05), symmetrical funnel plot, and fail-safe N of 137. However, heterogeneity among studies was present, with I2 value of 66.7%, Q = 41.663 (p <0.001); thus, Random Effect (RE) model was used. The RE model showed a significant positive effect of the NPWT on chronic wound healing, with z = 3.014, p = 0.003, 95% CI 0.085 to 0.400. The observed effects include decreased rate of surgical site infection, controlled inflammation, edema, and exudate, as well as increased tissue with varying forest plot size, as demonstrated by the small effect size (ES = 0.24, 95% CI -0.26 to 0.79, p <0.05). Conclusion: The analysis results show that the standard low pressure of 80-125 mmHg could improve microcirculation and accelerate the healing process of chronic wounds. Therefore, applying the NPWT program could be an alternative to nursing interventions. However, it should be carried out by competent wound nurses who carry out procedure steps, implement general patient care, and give tips on overcoming device problems and evaluation. PROSPERO registration number: CRD42022348457

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Effectiveness of negative pressure wound therapy on chronic wound healing: A systematic review and meta-analysis

Burhan¹,

Khusein²,

Sebayang³

2022

Belitung Nurs J

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“…It should be noted, however, that NPWT may provide other benefits beyond wound closure. For example, treatment with NPWT significantly reduced leukocyte count, pain, and systemic inflammatory response; discharge criteria and granulation tissue were also present significantly earlier when using this treatment [ 156 ]. Whether NPWT increases or decreases blood flow and oxygenation in treated tissues is controversial, as different investigative techniques have yielded varying results.…”

Section: Treatment Strategiesmentioning

confidence: 99%

Diabetic Wound-Healing Science

et al. 2021

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Diabetes mellitus is an increasingly prevalent chronic metabolic disease characterized by prolonged hyperglycemia that leads to long-term health consequences. It is estimated that impaired healing of diabetic wounds affects approximately 25% of all patients with diabetes mellitus, often resulting in lower limb amputation, with subsequent high economic and psychosocial costs. The hyperglycemic environment promotes the formation of biofilms and makes diabetic wounds difficult to treat. In this review, we present updates regarding recent advances in our understanding of the pathophysiology of diabetic wounds focusing on impaired angiogenesis, neuropathy, sub-optimal chronic inflammatory response, barrier disruption, and subsequent polymicrobial infection, followed by current and future treatment strategies designed to tackle the various pathologies associated with diabetic wounds. Given the alarming increase in the prevalence of diabetes, and subsequently diabetic wounds, it is imperative that future treatment strategies target multiple causes of impaired healing in diabetic wounds.

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“…Los resultados fueron equiparables al del sistema comercial (8). Gonzales I et al (9) comparo terapia asistida por vacío comercial y artesanal en ulceras crónicas de miembro inferiores donde el recuento de leucocitos, la respuesta inflamatoria sistémica y el dolor fueron significativamente menor en el grupo tratado con el sistema artesanal (p < 0.05), así como también el tejido de granulación estuvo presente tiempo antes en el grupo artesanal (p < 0.05).…”

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Uso de terapia de cierre asistido por vacío artesanal para el tratamiento de defecto de partes blandas en paciente postoperado de osteomielitis crónica en tibia

Ramos¹,

Terán²,

Mostacedo³

2022

Rev. Inv. Inf. Sal.

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La adecuada cobertura de partes blandas resulta importante en el tratamiento de la osteomielitis crónica. Existen muchas técnicas para el cierre de heridas, desde el cierre primario hasta la utilización de colgajos. El sistema de cierre asistido por vacío es un método que aplica presión negativa aumentando la proliferación del tejido de granulación. Un paciente masculino de 29 años, internado en el servicio de Ortopedia y Traumatología del Hospital de Clínicas, diagnosticado con osteomielitis crónica en diáfisis de tibia izquierda. Se realizó limpieza quirúrgica quedando un defecto de partes blandas de 6 x 3 cm con exposición de tejido óseo. Fabricamos un aparato de presión negativa, el cual con materiales accesibles y económicos lo aplicamos sobre la herida durante 3 semanas, realizando cambios de la esponja cada semana. Recibió antibióticos acorde a cultivo y antibiograma. Se logró cobertura completa del hueso expuesto por tejido de granulación, posteriormente injerto de piel. El sistema VAC revolucionó el manejo de las heridas, es un método de tratamiento seguro, no invasivo y con complicaciones menores. Sin embargo, el tiempo necesario de uso, materiales y los altos costos de alquiler hacen difícil su utilización en nuestro hospital, al cual en su mayoría acuden pacientes de escasos recursos que no pueden acceder a opciones de tratamiento costosos. En conclusión, nuestro VAC artesanal resulto ser una herramienta segura, eficaz, económica y de fácil uso en el manejo de defecto de partes blandas. Además de brindar otra alternativa de tratamiento con buenos resultados.

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Handcrafted Vacuum‐Assisted Device for Skin Ulcers Treatment Versus Traditional Therapy, Randomized Controlled Trial

Cited by 10 publications

References 42 publications

Effectiveness of negative pressure wound therapy on chronic wound healing: A systematic review and meta-analysis

Effectiveness of negative pressure wound therapy on chronic wound healing: A systematic review and meta-analysis

Diabetic Wound-Healing Science

Uso de terapia de cierre asistido por vacío artesanal para el tratamiento de defecto de partes blandas en paciente postoperado de osteomielitis crónica en tibia

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