Hand sanitiser‐associated ocular chemical injury in children

Rodríguez‐Ares, María Teresa; Touriño, Rosario; Lamas-Francis, David; Martínez-Pérez, Laura; Bustelo, Marina; González, Francisco

doi:10.1111/jpc.15395

Cited by 2 publications

(1 citation statement)

References 6 publications

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“…[ 16 ] Our study revealed an increase in the proportion of chemical injuries partly due to an increased number of sanitizer-related ocular injuries rather than occupation related, in keeping with recent reports in the literature. [ 17 18 ] Interesting to note, there was a significant increase in dry eye syndrome. It is hypothesized that patients under lockdown are at risk of ocular surface alterations due to a number of predisposing factors.…”

Section: Discussionmentioning

confidence: 99%

The impact of COVID-19 pandemic on ophthalmic referrals within a tertiary academic center in Oman

Busaidi

Mal

Rafei

et al. 2021

Middle East Afr J Ophthalmol

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PURPOSE: To investigate the impact of coronavirus infection disease-19 (COVID-19) pandemic on ophthalmic referrals within an academic tertiary center in Oman. METHODS: Retrospective chart review of internal referrals received and evaluated by the ophthalmology department between March 1and August 31, 2020 (COVID-19 period) compared to a corresponding period in 2019 (pre COVID-19). Data included patient demographics, referral details, ocular diagnosis, intervention, and discharge plan. RESULTS: Referral volume significantly decreased by 58.2%; from 2019 prepandemic to 510 ( P = 0.001), with the lowest in April and May 2020. Patient demographics did not differ significantly, but “urgent” referrals reduced by 96.2% ( P < 0.001). Main reasons for referrals were reduced vision and screening in both periods. During pandemic, referrals for screening purposes increased from 30.3% to 37.9% ( P = 0.013) and for reduced vision decreased from 30% to 23.3% ( P = 0.021). Dry eye syndrome increased in frequency during 2020 (from 2.9% to 7.3%, P = 0.002) but cataracts and conjunctivitis both decreased (from 4.7% to 2.1%, P = 0.046 and from 2.3% to 0.3%, P = 0.013, respectively). Ocular trauma remained stable (from 0.8% to 0.3%, P = 0.456), but the proportion of chemical injuries increased by 13.7% ( P = 0.025). There was a drastic decrease in interventions from 37% to 26.1% ( P < 0.001) and an increase in discharge rate from 61.2% to 75.8% ( P < 0.001). CONCLUSION: The impact of COVID-19 pandemic on ophthalmic referrals within a tertiary academic centre in oman referral reductions and changes in pattern and characteristics as an epiphenomenon of COVID-19 reflect the extent of impact specifically in an Omani context. This information is vital for planning proper resource utilization, the adoption of innovative care delivery, and improving referral system pathways.

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Section: Discussionmentioning

confidence: 99%

The impact of COVID-19 pandemic on ophthalmic referrals within a tertiary academic center in Oman

Busaidi

Mal

Rafei

et al. 2021

Middle East Afr J Ophthalmol

View full text Add to dashboard Cite

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Effectiveness of plant-based hand sanitizer incorporating Quercus infectoria gall extract

Waen-ngoen,

Wunnoo,

Nwabor

et al. 2023

Journal of Applied Microbiology

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Aims Quercus infectoria (Qi), a traditional herbal plant with a broad spectrum of activities on multidrug-resistant bacteria, has been developed for hand sanitizer applications. Methods and Results Antimicrobial activity was evaluated using agar-well diffusion and broth microdilution method. Bactericidal activity was determined following the European Standard 1276 antibacterial suspension test. Neutralization assay was performed to assess antirespiratory syncytial virus. Safety, stability, and skin permeation of Qi hand gel was investigated. Qi hand sanitizer gel inhibited microorganisms ranging from 99.9% to 99.999% against Enterococcus faecalis, Staphylococcus aureus, methicillin-resistant Staph. aureus, Staph. epidermidis, Staph. pseudintermedius, Staph. saprophyticus, Streptococcus pyogenes, Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Candida albicans. A significant reduction in main human dermatophytes including Microsporum canis, M. gypseum, and Talaromyces marneffei of ∼50% was observed (P < .05). Qi hand sanitizer gel inactivated >99% viral particles entering human laryngeal epidermoid carcinoma cells in a dose-dependent manner. Scanning electron micrographs further illustrated that Qi hand sanitizer gel disrupted microbial cell membrane after 1-min contact time resulting in cell death. Qi hand sanitizer gel delivered emollient compounds through simulated human skin layers and showed no cytotoxicity on fibroblast cells. Moreover, Qi hand sanitizer gel demonstrated stability under extreme conditions. Conclusions Qi hand sanitizer gel was able to inhibit various microorganisms including bacteria, dermatophytes, and virus.

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Hand sanitiser‐associated ocular chemical injury in children

Cited by 2 publications

References 6 publications

The impact of COVID-19 pandemic on ophthalmic referrals within a tertiary academic center in Oman

The impact of COVID-19 pandemic on ophthalmic referrals within a tertiary academic center in Oman

Effectiveness of plant-based hand sanitizer incorporating Quercus infectoria gall extract

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