Hand eczema-Clinical patterns and role of patch testing

Kishore, Nanda B; Belliappa, A D; Shetty, Neeta; Sukumar, D; Ravi, Saranya

doi:10.4103/0378-6323.16244

Cited by 24 publications

(42 citation statements)

References 4 publications

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“…11 Similarly, in a study by Kishore et al the positive patch test was seen in 82% of the patients and Potassium dichromate was the most common sensitizer testing positive in 26% of the patients while nickel was the next common testing positive in 18% of the patients. 17 A study by Kaur and Sharma in Chandigarh found that 53.1% of the patients with hand eczema were sensitive to metals. Of these, nickel, cobalt and chromate sensitivity were seen in 40.6%, 31.2% and 21.8% patients respectively.…”

Section: Discussionmentioning

confidence: 99%

“…Similar findings were seen in number of studies. [22][23][24] Greater preponderance of hand eczema in this subset of population is possibly because of increased exposure to wet work, exposure to detergents and use of jewellery. Detergents are an important source of sensitization, proven by positive patch test results to nickel, cobalt and PPD among patients with history of exposure to detergents.…”

Section: Discussionmentioning

confidence: 99%

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Patch testing in hand eczema: a cross-sectional study from a teaching hospital of North India

Qayoom¹,

Rather²,

Khan³

2018

Int J Res Med Sci

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Background: Hand eczema is a common dermatological disorder in different occupational groups with multifactorial etiology. Patch Testing serves as an important tool for identifying responsible allergens.Methods: The study was conducted in the Department of Dermatology, SKIMS-MCH, Srinagar for duration of one year from June 2016 to June 2017. Patients of either gender with hand eczema, aged 18 years and above, presenting to outpatient department were enrolled in the study. After taking informed written consent from patients, a detailed history was taken, and clinical examination was performed on first visit. Patch testing with Indian Standard Series was performed a fortnight after complete resolution of signs and symptoms of eczema and after complete withdrawal of the drugs.Results: Out of 116 patients 60 (51.7%) were males and 56 (48.3%) were females. Male to female ratio was 1.07:1. Mean age of presentation of females was 35.42±12.52years and of males was 49.2±10.01years. The commonest allergen was Nickel sulphate (23.2%) followed by Potassium dichromate (15.1%). Nickel sulphate was most common allergen in females while Cobalt sulphate and Paraphenylene diamine were most common allergens in males. House wives (36.2%) and farmers (11.2%) were occupations with high frequency of hand eczema.Conclusions: Patch testing in clinically diagnosed cases of hand eczema can play a vital role in not just the confirmation of the label but can also reduce the socio-economic burden on such patients.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Patch testing in hand eczema: a cross-sectional study from a teaching hospital of North India

Qayoom¹,

Rather²,

Khan³

2018

Int J Res Med Sci

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“…5 This is because of the variety of agents that they come in contact with which may act either as irritants or allergens such as vegetables, soaps, detergents, in addition to the trauma of rubbing and scrubbing. 6 In the present study, it was shown that all age groups can develop hand eczema. However, the majority of the patients were in the age group of 20-30 years which formed 36% of the study population.…”

Section: Discussionmentioning

confidence: 92%

“…5 The findings of our study are also in accordance with the study done by Kishore et al who observed that majority of the patients presented with fissuring. 6 In this study, it was found that 75% of the patients had patch test positivity to various allergens. In the past, patch testing has yielded positive results ranging from 50% to 92.5%.…”

Section: Discussionmentioning

confidence: 96%

A study of profile of contact dermatitis in housewives with reference to vegetables, soaps and detergents

et al. 2018

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Background: Contact dermatitis in housewives is a common dermatological problem as almost all housewives have to handle vegetables, fruits, soaps and detergents. The purpose of this project was to study etiologic profile of contact dermatitis occurring in housewives.Methods: One hundred housewives, clinically diagnosed as having contact dermatitis, were randomly selected for the study. Each patient was then subjected to patch testing using the Indian standard battery and certain indigenously prepared antigens i.e. vegetables, soaps and detergents. The first reading was taken 60 minutes with second reading at 96 hours. Reading equal to or more than 1+ was considered to be a positive test.Results: Majority patients were in the age group of 20-30 years. Morphological diagnosis was wear and tear dermatitis in 43%, discoid eczema (19%), fingertip eczema (16%), hyperkeratotic (15%) and pompholyx (7%). Nickel sulphate was found to be the commonest allergen (19%) followed by para-phenylenediamine (8%), fragnance mix (7%), Balsam of Peru (6%), parthenium (6%) and cobalt (5%). Amongst vegetables, the commonest culprit was garlic. Allergic reaction to detergents was positive in 13% patients. Forty-four percent of the cases tested positive to the suspected allergen whereas 31% patients tested positive for allergens not initially suspected of causing contact dermatitis in them.Conclusions: Thus patch testing is an important tool in establishing the cause of allergic contact dermatitis of the hands in housewives in whom the hand eczema is multifactorial. This enables the correct etiological diagnosis and proper management of housewives with hand dermatitis.

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“…Kishore N.B. et al 14 have reported potassium dichromate as common sensitizer testing positive in 26% of the patients of Hand eczema. Cobalt sensitivity was seen in 6 (15.38%) of the male patients and 2 (22.22%) female patients.…”

Section: (25 Years)mentioning

confidence: 99%

Study of Patch Testing in Allergic Contact Dermatitis in Hands and Feet

A¹,

Sudheer²,

Paidipally³

et al. 2016

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Contact Dermatitis (CD) is an altered state of skin reactivity induced by exposure to an external agent. According to the mechanism of elicitation, the following types of contact reactions may be distinguished: Allergic Contact Dermatitis (ACD), Irritant Contact Dermatitis (ICD), Phototoxic and Photo Allergic Contact Dermatitis and Immediate Type Contact Reactions or Immune Contact Urticaria. ACD is a delayed-type hypersensitivity reaction that is elicited when the skin comes in contact with a chemical to which an individual has previously been sensitised. Patch testing remains the gold standard for diagnosing ACD. This study focuses on identifying the allergens causing ACD of hands and feet. METHODStudy was conducted in Osmania General Hospital, Hyderabad, over a period of 12 months' duration. Patients suspected to have contact dermatitis were subjected to patch testing. Based on the history, clinical signs and symptoms, a total of 50 patients were shortlisted in 12 months' duration. RESULTOur study showed that the most common allergen showing patch test positivity in both males and females were metals like chromates followed by cosmetics and others. Patients showed significant improvement in their dermatitis after avoidance of the offending agent. CONCLUSIONPatch test is the method of choice and the "gold standard" in the detection of contact allergy and allergic contact dermatitis.

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Hand eczema-Clinical patterns and role of patch testing

Cited by 24 publications

References 4 publications

Patch testing in hand eczema: a cross-sectional study from a teaching hospital of North India

Patch testing in hand eczema: a cross-sectional study from a teaching hospital of North India

A study of profile of contact dermatitis in housewives with reference to vegetables, soaps and detergents

Study of Patch Testing in Allergic Contact Dermatitis in Hands and Feet

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