Hand eczema: causes, course, and prognosis I

Veien, Niels K.; Hattel, Thais; Laurberg, Grete

doi:10.1111/j.1600-0536.2008.01345.x

Cited by 96 publications

(82 citation statements)

References 16 publications

(14 reference statements)

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“…Two studies found a positive association between severity and smoking (32,41); one of these was performed in an occupational setting, and the results are reported above (32). One study found no association between tobacco smoking and HE severity (42), and one study found that HE was more severe in non-smoking housewives (33). Two of these studies concerning severity were from occupational settings, and are therefore listed in Table 1 as well as in Table 2.…”

Section: Results Of Studies On the Effect Of Tobacco Smoking On He Sementioning

confidence: 99%

“…Four studies examined the relationship between HE severity and smoking (Table 3). Two of the studies found more severe HE in smokers than in non-smokers (32,41), one found more severe HE in non-smokers (33), and one found no association (42).…”

Section: Discussionmentioning

confidence: 99%

“…The relationship between subclassification of HE and smoking was evaluated in five studies only (27,(42)(43)(44)(45); they found no significant association (42,45), a positive association with erythematous lesions and vesicles (27), a positive association with palmar eczema (43), or a positive association with combined irritant/allergic HE (44). However, HE is a heterogeneous disease: it may be that there are differences between the various subclasses of HE and factors such as smoking.…”

Section: Discussionmentioning

confidence: 99%

“…Ten studies were cross-sectional studies (29, 34-40, 43, 44), in which it is not possible to draw conclusions on causality, for which prospective cohort studies are required (9,27,31,41,42). The follow-up period in the cohort studies ranged from 1 to 9 years, and loss to follow-up, which can cause significant bias, varied in the studies from 0% to 51%.…”

Section: Discussionmentioning

confidence: 99%

“…The studies were conducted differently: 10 were cross-sectional studies (29, 34-40, 43, 44), five were case-control studies (28,30,32,33,45), and five were cohort studies (9,27,31,41,42), complicating a direct comparison.…”

Section: Discussionmentioning

confidence: 99%

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Tobacco smoking and hand eczema – is there an association?

et al. 2015

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SummaryBackground. Numerous risk factors have been suggested for hand eczema. This systematic review evaluates the association between tobacco smoking and hand eczema. Objective. To review the literature systematically on the association between smoking and hand eczema. Methods. The PubMed and EMBASE databases were searched up to 27 January 2015 for articles on the association between tobacco smoking and hand eczema, including human studies in English and German only. Experimental studies, studies on tobacco allergy, case reports, reviews and studies on second-hand smoking were excluded. Results. Twenty articles were included. Among studies in occupational settings, three of seven found a statistically significant positive association between tobacco smoking and hand eczema prevalence rate, as did four of eight population-based studies. The association was stronger for studies in occupational settings than for population-based studies. No studies reported tobacco to be a clear protective factor for hand eczema. Two of five studies regarding severity found a positive association between smoking and hand eczema severity. Conclusion. Overall, the data indicate that smoking may cause an increased frequency of hand eczema, particularly in high-risk occupations. However, data from studies controlling for other risk factors are conflicting, and few prospective studies are available. Studies controlling for other risk factors are needed, and information regarding the diagnosis of subclasses of hand eczema, as well as severity, may be important.

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Section: Results Of Studies On the Effect Of Tobacco Smoking On He Sementioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%