Hand dermatitis aggravated by contact allergy to methylisothiazolinone in protective nitrile gloves

André, R; Tehrany, Yassaman Alipour; Bugey, Aurélie; Edder, Patrick; Piletta, Pierre

doi:10.1111/cod.14173

Cited by 8 publications

(2 citation statements)

References 6 publications

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“…Gloves continue to be a source of known allergens related to rubber accelerators and also newly described allergens. These include 1,3-diphenylguanidine (DPG), benzisothiazolinone and cetylpyridinium chloride (CPC, an antimicrobial agent that coats the inside of some surgical gloves) [47,48]. These should be patch tested in healthcare workers with hand dermatitis who use sterile surgical gloves if available.…”

Section: Preventive Equipment and Products Amplified By Covid-19mentioning

confidence: 99%

New causes of occupational allergic contact dermatitis

Clynick,

Holness

2023

Current Opinion in Allergy &Amp; Clinical Immunology

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Purpose of review Occupational allergic contact dermatitis (OACD) is an important work-related skin disease. Information about the causative agents comes from many sources, including patch test databases, registries, case series and case reports. This review summarizes new information about common causative allergens and diagnosis. Recent findings Common causes of OACD include rubber components, epoxies and preservatives. New exposure sources for these allergens continue to be described. Often these exposure sources are related to the changing world around us, such as allergens related to smartphones and technology, and personal protective equipment-related exposures during the COVID-19 pandemic. New allergens are also being described, some of which are related to known allergens (e.g. a new epoxy or acrylate component). Accurate diagnosis is critical to effective management of OACD, which may include removing the worker from exposure to the causative allergen. Safety data sheets may not contain complete information and patch testing with specialized series of allergens and workplace materials may be necessary. Summary This review provides current evidence about causes of OACD and important aspects of diagnosis. This is important for clinical practice to ensure cases of OACD are not missed.

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Section: Preventive Equipment and Products Amplified By Covid-19mentioning

confidence: 99%

New causes of occupational allergic contact dermatitis

Clynick,

Holness

2023

Current Opinion in Allergy &Amp; Clinical Immunology

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“…A complete history of allergic responses should be obtained from potential patients. Nitrile is better than latex because it is thinner than latex and still does not tear off, and its frequency of allergic reaction is much lower than that of latex [6]. A type of symptomatic dermographism known as glove-related hand urticaria is believed to be brought on by a mix of shearing forces from repeated donning and removing of gloves and direct pressure from the glove.…”

Section: Introductionmentioning

confidence: 99%

Comparative Assessment of Hypersensitivity Reactions on Use of Latex and Nitrile Gloves Among General Dental Practitioners: A Cross-Sectional Study

Naranje,

Paul,

Parate

et al. 2023

Cureus

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BackgroundLatex gloves are used more frequently by dental, medical, and other health workers and their allergy has also increased as a result, dentists are frequently exposed to latex or nitrile gloves for extended periods. This prolonged exposure often leads to local symptoms such as itching and erythema rashes. However, some dentists experience more severe systemic reactions, including swelling, wheezing, breathlessness, and even an increase in blood pressure. Latex gloves have recently been replaced with nitrile gloves, powder-free latex gloves, and other preventive measures to avoid allergies. Latex allergies are more common than nitrile allergies, as they are hypoallergic with properties such as tear-resistant and provide an equivalent level of defense against various dental materials and procedures. Women experience more allergic reactions than men. Not only are dentists exposed to this allergy but the patient can also be exposed during the procedure. This study aimed to assess hypersensitive reactions to the use of latex and nitrile gloves among general dentist practitioners and dental students. MethodsA cross-sectional study was conducted in Wardha, Maharashtra, India, to evaluate allergic reactions to latex and nitrile gloves among general dental practitioners and dental students at college. A questionnaire-based study was conducted with a sample size of 356. The self-administered survey inquiries about glove compliance, the time they wear the gloves, regular glove use, and problems related to latex or nitrile contact. In addition, dentists and dental students' personal histories of allergies to medications, dental materials, disinfectants, or other chemicals were noted, as well as signs and symptoms they experienced from prolonged contact with gloves. ResultThe total number of responses collected was 356. The investigated dentists were 274 and 82 were students, out of which 122 (34.3%) were male and 234 (65.7%) were female. Responses showed that 224 (62.92%) used latex gloves, and 132 (37.08%) used nitrile gloves. Among 356 participants 175 showed symptoms by the use of both latex and nitrile gloves, out of which 85.14% showed allergy to latex and 14.85% to nitrile gloves. All 175 individuals showed type IV hypersensitivity, and none of them showed type I. ConclusionLatex gloves are not the only option for dentists who experience itching when wearing gloves; they can also use powered-free latex gloves and nitrile gloves or take precautions such as not using oil-based cream, washing their hands, or taking pharmaceuticals such as cetirizine, pheniramine maleate, etc. However, when symptoms worsen and include erythema, swelling, wheezing, and in some cases, anaphylactic shock may occur they tend to use alternative gloves.

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Contact Dermatitis to Isothiazolinone Preservatives

Latheef

Wilkinson

2023

Curr Derm Rep

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Hand dermatitis aggravated by contact allergy to methylisothiazolinone in protective nitrile gloves

Cited by 8 publications

References 6 publications

New causes of occupational allergic contact dermatitis

New causes of occupational allergic contact dermatitis

Comparative Assessment of Hypersensitivity Reactions on Use of Latex and Nitrile Gloves Among General Dental Practitioners: A Cross-Sectional Study

Contact Dermatitis to Isothiazolinone Preservatives

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