Hamsters and Gerbils

McKeon, Gabriel P; Nagamine, Claude M.; Felt, Stephen A.

doi:10.1002/9781119108610.ch7

Cited by 2 publications

(1 citation statement)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Уровень билирубина в крови повышается также при усиленном распаде гемоглобина. Помимо упомянутых показателей, желчные кислоты также могут служить полезным маркером хронического гепатита у песчанок [30]. Фермент аспартатаминотрансфераза выделяется из поврежденных клеток печени и мышц.…”

Section: результаты и обсуждениеunclassified

Variability of blood biochemical parameters and establishment of reference intervals in preclinical studies. Part 10: mongolian gerbils

Miroshnikov,

Sultanova,

Kovaleva

2023

Lab Anim Sci Rus

View full text Add to dashboard Cite

Gerbils as a type of laboratory animals are widely used as experimental models in a number of areas of biomedical research. This type of laboratory animals is relatively easy to maintain and handle. They are an alternative test system among rodents such as mice and rats. They are most often used in the study of cerebral ischemia or stroke, behavioral research, aging processes, the development of oncological diseases, as well as the study of parasitic, viral and bacterial infections, studies of the mechanisms and therapy of epileptic seizures and metabolic disorders such as obesity and diabetes mellitus. The aim of this work was to create a database of reference intervals of biochemical parameters of normal healthy mature Mongolian gerbils with further use in daily routine laboratory practice in preclinical centers. The data that were used to form the reference intervals were obtained from intact animals in “Home оf Pharmacy”. All manipulations and experiments were approved by the bioethical commission. The study involved 20 males and 20 females (non-pregnant excluding the estrous cycle phase) of Mongolian gerbils. The age of the animals corresponded to the range of 6–8 weeks, the body weight of males and females was within 60 g. The levels of the following parameters were determined in the blood serum of animals: creatinine, urea, alanine aminotransferase, aspartateaminotransferase, alkaline phosphatase, cholesterol, triglycerides, total protein, albumin, glucose, total bilirubin, the number of globulins was calculated, as well as the ratio of albumin/globulins. The obtained ranges of males and females had no statistical difference between them. These intervals were analyzed for comparison with other reference intervals of gerbils found in the scientific literature, as well as with ranges of similar indicators characteristic of humans. Norms of biochemical parameters of blood serum of gerbils are an important tool necessary for monitoring animal health during biomedical research, monitoring the dynamics of modeling pathological conditions in animals and studying the safety of new pharmacological agents. An important aspect in preclinical research is the creation of any reference intervals of laboratory animals in each scientific center separately. This is due to a large number of pre-analytical, analytical and post-analytical features, as well as minimizing the risk of misinterpretation of the data obtained during biomedical research.

show abstract

Section: результаты и обсуждениеunclassified

Variability of blood biochemical parameters and establishment of reference intervals in preclinical studies. Part 10: mongolian gerbils

Miroshnikov,

Sultanova,

Kovaleva

2023

Lab Anim Sci Rus

View full text Add to dashboard Cite

show abstract

Approaches to common conditions of the gastrointestinal tract in pet hamsters

Baldrey

2021

Companion Animal

View full text Add to dashboard Cite

Hamsters are popular pets in the UK. The Syrian or Golden hamster (Mesocricetus auratus) is the best known species in the pet trade, with a variety of dwarf species also encountered. Gastrointestinal disease occurs frequently, and diarrhoea is a common presenting complaint. This is most often associated with bacterial or parasitic infection, but can also be related to neoplasia or the use of certain antibiotics. Initial stabilisation of the hamster with diarrhoea should include provision of a warm stress-free environment, fluid therapy, nutritional support with an appropriate critical care diet and analgesia. Following a full history and clinical examination, further diagnostic steps include faecal parasitology and microbiology, routine biochemistry and haematology, radiography with or without positive contrast, and abdominal ultrasound. Indications for surgery include evidence of intestinal obstruction or prolapsed intussusception. This article gives an overview of the most common gastrointestinal diseases encountered in hamster species and provides a guide of how to logically approach the investigation and treatment of these cases, achievable in general practice.

show abstract

Hamsters and Gerbils

Cited by 2 publications

References 54 publications

Variability of blood biochemical parameters and establishment of reference intervals in preclinical studies. Part 10: mongolian gerbils

Variability of blood biochemical parameters and establishment of reference intervals in preclinical studies. Part 10: mongolian gerbils

Approaches to common conditions of the gastrointestinal tract in pet hamsters

Contact Info

Product

Resources

About