When the normal bundle N Z =X is convex with a minor assumption, we prove that genus 0 GW-invariants of the blow-up Bl Z X of X along a submanifold Z , with cohomology insertions from X , are identical to GW-invariants of X . Under the same hypothesis, a vanishing theorem is also proved. An example to which these two theorems apply is when N Z =X is generated by its global sections. These two main theorems do not hold for arbitrary blow-ups, and counterexamples are included.