Hamartoma of the urinary bladder in a 15-year-old boy

Abstract

Hamartoma of the bladder is an unusual entity described in only eleven patients to date. It may present as painless hematuria, irritative urinary tract symptoms, or inability to void or it may be diagnosed incidentally. Hamartoma of the bladder may be isolated or occur as part of a syndrome. No isolated bladder hamartoma to date has shown malignant potential. We describe here a bladder hamartoma in a 15-year-old boy.

Bladder hamartoma in Peutz-Jeghers syndrome: a rare case report

“…They are, however, extremely rare in the urinary bladder [8,9]. Since the first case reported by Davis in 1949 [10], only twelve cases (Table 1), to the best of our knowledge, have been reported in the literature up to now [11,12], with only one case found in the literature associated with PJS [13]. Most cases tend to occur near to the trigone [8,9], while the mass in our case was at the bladder neck.…”

“…With the rarity of the lesion, they set guidelines for the follow-up schedule of such patients. As such, certain reported cases have advocated cystoscopy to be done every three months for a year, then yearly for four years [13], a follow-up examination ranging from four months to five years [14], or simply a long-term periodic cystoscopy as surveillance-since the malignant potential of these lesions is as such unknown [11]. Our patient has had only one check cystoscopy done 3 months after the resection, and no growths were seen on check cysto.…”

Urinary bladder hamartoma: A case of one of the rarest entities reported in urology

“…Most of the cases are diagnosed in the context LUTS, gross haematuria or suprapubic pain. In this regard, our patient was the first case reported as an incidental finding in an otherwise asymptomatic adult [2,3]. Therefore, this presentation is not in agreement with solely proposed pathophysiology by Davis, that postulated that UBH may be a result of a chronic inflammatory process [1].…”

“…All the reported cases had a benign behaviour, including invasive hamartomas, and no recurrences was seen in isolated UBH, although the surveillance described were not superior of five years [2,3]. For this reason, although cystoscopy should be the method of choice for surveillance, there is no agreement regarding the schedule and time of follow-up, with some authors advocating that cystoscopy should be performed every three months for a year and then yearly for four years or simply a long-term periodic cystoscopy as surveillance for recurrence.…”

“…Although it may occur in any body site, Urinary Bladder Hamartoma (UBH) is extremely rare. The first case of UBH was reported in 1949 by Davis [1] and, ever since, only fourteen other cases (including our patient) have been reported, as an isolated entity, or as part of a hereditary syndrome, such as Peutz-Jeghers syndrome, Beckwith-Wiedemann syndrome, Goldenhar Syndrome or multiple hamartomatous syndrome, also known as Cowden disease [2,3].…”