Hamartoma of the spleen with haematological symptoms

Beham, Alfred; Hermann, Wolfgang; Vennigerholz, Felizitas; Schmid, C

doi:10.1007/bf00781712

Cited by 20 publications

(7 citation statements)

References 12 publications

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“…Many cases were documented as case reports or in small series. To date, in excess of 130 splenic hamartomas have been documented in the English literature 1 –63 . Overall, hamartomas were detected over a wide age range (11 months to 86 years) and with a mean age of 47 years at presentation.…”

Section: Discussionmentioning

confidence: 99%

Splenic Vascular Lesions: Unusual Features and a Review of the Literature

Lam¹,

Yip²,

Peh

1999

Aust. N.Z. J. Surg.

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Hamartoma and peliosis are uncommon splenic lesions. Approximately 120 splenic hamartomas and 40 splenic peliosis have been reported in the English literature. In the present study, a unique case of multiple splenic hamartomas with peliosis was reported. The splenic lesions were incidental findings in a 36-year-old man with ruptured sarcomatoid renal cell carcinoma. They were diagnosed clinically as metastatic renal cell carcinoma. On pathological examination, peliosis was noted in the splenic hamartomas as well as in the splenic parenchyma. In addition, the clinicopathological features of five other splenic hamartomas (including one giant hamartoma) noted in our department were presented. A re-evaluation of the features of the splenic hamartomas documented in the English literature was also done.

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Section: Discussionmentioning

confidence: 99%

Splenic Vascular Lesions: Unusual Features and a Review of the Literature

Lam¹,

Yip²,

Peh

1999

Aust. N.Z. J. Surg.

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“…The diameter and weight show a gender-specific correlation to the mean weight and the diameter of the lesions, which is higher in women than in men, so that women more often have symptoms related to the lesion mass than men. Hamartoma of the spleen can occur at any age, but the mean age is 37.5 years for women and 27 years for men [2]. Extramedullary haematopoiesis is more frequent in paediatric patients and is an unusual diagnosis in adults [4].…”

Section: Discussionmentioning

confidence: 98%

“…We report a rare case of the incidental finding of a splenic hamartoma with extramedullary erythropoiesis without any clinical or haematological symptoms in a 70-yearold man. Only a few cases of hamartoma with [2][3][4][5][6][7][8]. A potential correlation between splenic hamartoma with extramedullary haematopoiesis and thalassaemia, polycythemia vera and myelofibrosis is mentioned [9,10].…”

Section: Discussionmentioning

confidence: 99%

“…Hamartomas of the spleen with extramedullary erythropoiesis are extremely rare. These lesions can show an association with haemolytic processes like thrombocytopenia and myeloproliferative diseases in some cases, but usually they are asymptomatic and are found incidentally [2][3][4][5][6][7].…”

Section: Introductionmentioning

confidence: 99%

“…Hamartomas of the spleen are uncommon tumour-like lesions that are mainly composed of vascular proliferative elements and were first described by Rokitansky in 1861 [1,2]. The most common neoplasms of the spleen are benign; haemangiomas are the most frequent, followed by splenic cysts and inflammatory pseudotumours.…”

Section: Introductionmentioning

confidence: 99%

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Incidental finding of a splenic hamartoma with tumour-like extramedullary erythropoiesis

Dolcet

Kornprat

Lindenmann

et al. 2011

Wien Med Wochenschr

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Hamartomas of the spleen are rare benign tumour-like lesions that tend to be asymptomatic incidental findings. Splenic hamartomas with tumour-like extramedullary erythropoiesis are extremely rare. A 70-year-old male patient with dyspnoea and a nodular intrapulmonary lesion morphologically verified by CT underwent fibre bronchoscopy, which showed a pea-shaped foreign body that was retrieved without complication. As a secondary finding, the CT showed a splenic lesion of about 8 cm in size. An MR study showed an expansive process in the center of the spleen. The patient was completely free of clinical symptoms. Because of the unknown nature and the high risk for spontaneous rupture of the lesion, a splenectomy was performed. The histological analyses revealed tumour-like extramedullary erythropoiesis of the spleen. The patient was discharged in good condition ten days postoperatively. A hamartoma of the spleen with extramedullary tumor-like erythropoiesis should be considered in the differential diagnosis of a splenic lesion.

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Splenic cord capillary hemangioma and anemia: Resolution after splenectomy

et al. 2006

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A 59-year-old female presented with isolated anemia and a splenic mass. Standard histology and immunohistochemical techniques categorized the splenic lesion as a cord capillary hemangioma. The patient's anemia resolved following splenectomy. Cord capillary hemangiomas are exceedingly rare with few reports in the literature. This is the first reported case of resolution of anemia after splenectomy for a vascular tumor of the spleen. Am. J. Hematol. 81:538-542, 2006. V V C 2006 Wiley-Liss, Inc.

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Hamartoma of the spleen with haematological symptoms

Cited by 20 publications

References 12 publications

Splenic Vascular Lesions: Unusual Features and a Review of the Literature

Splenic Vascular Lesions: Unusual Features and a Review of the Literature

Incidental finding of a splenic hamartoma with tumour-like extramedullary erythropoiesis

Splenic cord capillary hemangioma and anemia: Resolution after splenectomy

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