Hamartoma of the lungs

Relationship Between Intrapulmonary and Endobronchial Cartilage-containing Tumours (so-called Hamartomata)

“…However, cases of intrapulmonary cartilage-containing tumours attached to the external wall of a small bronchus have been reported by Franco (1958), Negre, Martin, and Loubatieres (1954), Nigam (1957), Novi (1955), Rubin and Berkman (1952), Sherrick (1952), Stein andPoppel (1955), and Weisel, Glicklich and Landis (1955). A few intrapulmonary cartilagecontaining tumours with a small bronchus entering their substance have been reported by Favre (1935), Mammer (1927, and Moller (1933).…”

“…The relation between these two types of cartilage-containing tumours is not well defined, and there is disagreement in the literature about this. Bianchi and Etchegoyen (1945), Liebow, (1952), McDonald, Harrington, and Clagett (1945), Roujeau (1961), Schaefer (1955), Santy, Berard, Breton, and Galy (1951), and Simon (1948) regard the intrapulmonary and endobronchial types of these cartilage-containing tumours as separate lesions, and Franco (1958) (1953), Donoghue, Andersen, and McDonald (1956), Filippi (1953), Green (1959), Hall (1948), Muendel and Yelin (1955), Postlethwait, Hagerty, and Trent (1948), Santoro and Nerone (1958), Rubin and Berkman (1952), Sherrick (1952), Stein and Poppel (1955), Terracol, Fabre, and Guerrier (1948), Young, Jones, Hughes, Foley, and Fox (1954), and Zeitlhofer (1954) take the opposite view and regard both the intrapulmonary and the endobronchial cartilaginous tumours as the same lesion.…”

Histogenesis of intrapulmonary and endobronchial hamartomas and chondromas (cartilage‐containing tumours): A hypothesis

“…The cartilage may contain bone and marrow spaces, and the connective tissue surrounding the cartilage may contain fat cells, bundles of smooth-muscle fibres, mucous glands, blood vessels and round cells. There is no connexion with the cartilage of bronchial rings (Postlethwait, Hagerty and Trent, 1948;Sutherland, Aylwin and Brewin, 1953).…”

“…This double layer is presumably derived from the wall of the small bronchus from which the tumour grew. The enucleation of intrapulmonary hamartomas frequently reveals the opening of a small bronchus in the tumour bed (Touroff and Seley, 1951 ;Corajod and BCrard, 1952). Other examples show a bronchus entering the substance of the tumour (Hammer, 1927;Moller, 1933), or attached to it (Rubin and Berkman, 1952;Sherrick, 1952;Negre, Martin and Loubatieres, 1954;Novi;Stein and Poppel, 1955;Weisel, Glicklich and Landis, 1955;Nigam, 1957;Franco).…”

Pulmonary `Hamartomata'

“…Nineteen of the 27 were men: a greater incidence among men is reflected in all other series and the preponderance varies from 2 to 3: 1 (Stein and Poppel, 1955;Jackson, McDonald, and Clagett, 1956). The youngest patient was 30 and the oldest 64 years.…”