‘Haltlose’ type personality disorder (ICD-10 F60.8)

Pharmacogenetic testing for the guidance of psychiatric treatment of a schizoaffective patient with haltlose personality disorder

“…Nevertheless, the most disturbing aspect of this patient's life was his complete selfish, hedonistic, irresponsible, drifting, and aimless lifestyle, along with a complete lack of hold on life or on his self. His life history led us to study the fascinating concept of Bleuler's haltlose personality disorder, 4 which came naturally as a comorbid diagnosis, based on some of the features now explained ( Table 1). The patient had been on many different combinations of benzodiazepines, antidepressants, mood stabilizers, and antipsychotics, aside from various attempts with psychotherapy, group therapy, occupational therapy, and electroconvulsive treatment.…”