“…Several reviews have appeared which by their title suggest a relationship between anaesthesia and liver function (Dykes, 1970;Editorial, 1972). There is evidence connecting liver dysfunction with halothane (Sherlock, 1971;Reed and Williams, 1972) and particularly with a second administration a few weeks after the first (Mushin, Rosen and Jones, 1971;Inman and Mushin, 1974;Wright et al, 1975). On the other hand, there have been many studies which do not support this connection, or which suggest the alternative possibility of viral hepatitis as a possible cause (National Halothane Study, 1966;Walton et al, 1972;Simpson, Strunin and Walton, 1973).…”