Halo‐1,2,3‐triazoles: Valuable Compounds to Access Biologically Relevant Molecules
Dylan Coelho,
Yoann Colas,
Mélanie Ethève‐Quelquejeu
et al.
Abstract:1,2,3‐triazole is an important building block in organic chemistry. It is also now well known as bioisostere for various functions, such as the amide or the ester bond, positioning it as key pharmacophore in medicinal chemistry and it has found applications in various fields including life sciences. Attention was first focused on the synthesis of 1,4‐disubstituted 1,2,3‐triazole molecules but 1,4,5‐trisubstituted 1,2,3‐triazoles have emerged as valuable molecules due to the possibility to expand the structural… Show more
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