Halloysite Nanotubes for Nanomedicine: Prospects, Challenges and Applications

Kushwaha, Swatantra Kumar Singh; Kushwaha, Neelottama; Pandey, Piyush; Fatma, Bushra

doi:10.1007/s12668-020-00801-6

Cited by 18 publications

(10 citation statements)

References 66 publications

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“…This study demonstrated the possibility of developing smart carriers, where the amount of drug release is minimal during delivery (pH 7.2), and when the tumor area is reached (pH 4.5-6.5), the drug release rate increases dramatically. It is interesting to note that pH-dependent processes are not only characteristic of complexes of nanostructures with organic structures [6], but are also observed for nonorganic polymer matrices, namely Carbon Nanotubes (CNTs) and Halloysite Nanotubes (HNTs) [7][8][9]. These studies demonstrate a large class of pH-dependent processes involving nano-biological assemblies, which stimulate further research in this area.…”

Section: Introductionmentioning

confidence: 86%

pH Responsive Tunable Plasmonic Resonators Based on Gold-Polysaccharide Nanocomposites

Kravchenko

Boltovets

Kovalenko

et al. 2022

The 3rd International Online-Conference on Nanomaterials

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Section: Introductionmentioning

confidence: 86%

pH Responsive Tunable Plasmonic Resonators Based on Gold-Polysaccharide Nanocomposites

Kravchenko

Boltovets

Kovalenko

et al. 2022

The 3rd International Online-Conference on Nanomaterials

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“…Another application of halloysite formulation for antimicrobial bone reparents is in dentistry, the halloysite-doped resins of teeth colors are being used for dental caries. Halloysite based adhesives increased the strength of the composites up to 50% [ 72].…”

Section: Bone Cement/ Dentist Fillersmentioning

confidence: 99%

Micro and Nano Clay-Biopolymer Composites for Drug Delivery

Jabeen¹

2022

Materials Research Foundations

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Clay-based biopolymers are among the most efficient and cost-effective composite materials that find applications in a variety of biomedical applications such as drug delivery. This chapter elaborates the different physical, chemical, and structural properties of clay biopolymeric composites, which makes them most reliable to use for the applications of drug delivery. The main focus of writing this chapter is to explore the composition, structural properties, and route of action of clay-based nanomaterials, along with elaborating the mechanism of the drug delivery system. The synthesis of clay-encapsulated drug formulation and their route of administration has been investigated in this chapter. Data for the synthesis of composites and in vitro study has also been included from the existing literature.

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“…As a result, so many efficient drug delivery systems have been reported in the recent decade. The surface of different types of the nanoscale materials such as metal-organic frameworks 21 , 22 , carbon 23 , 24 halloysite nanotubes 25 , 26 , and metallic nanoparticles 27 – 29 have been functionalized with antibodies to add targeting function to their systems.…”

Section: Introductionmentioning

confidence: 99%

A magnetic antibody-conjugated nano-system for selective delivery of Ca(OH)2 and taxotere in ovarian cancer cells

et al. 2022

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An efficient strategy for cancer therapy is presented, in which a tumor mass is initially pretreated with calcium hydroxide, then treated with Taxotere (TXT). In this regard, an advanced delivery system based on iron oxide nanoparticles has been designed. The surface of nanoparticles was functionalized with sortilin (SORT-1, a human IgG1 monoclonal antibody) that specifically encodes caov-4 ovarian cancerous cells. Plasmonic heating of the incorporated gold nanoparticles in polyvinyl alcohol (PVA) has been exploited to control the release process of TXT. The in vitro, ex vivo and in vivo experiments have exhibited high efficacy of a seven-day pretreatment by Ca(OH)2 plus 14 days treatment program by Ca(OH)2@Fe3O4/PVA/Au-SORT nano-therapeutics, where more penetration ratio resulted in tumor growth inhibition by ca. 78.3%. As a result, due to showing high values of the anti-tumor properties and biosafety, the presented pretreatment strategy is suggested for more effective treatment on the aged tumors.

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Halloysite Nanotubes for Nanomedicine: Prospects, Challenges and Applications

Cited by 18 publications

References 66 publications

pH Responsive Tunable Plasmonic Resonators Based on Gold-Polysaccharide Nanocomposites

pH Responsive Tunable Plasmonic Resonators Based on Gold-Polysaccharide Nanocomposites

Micro and Nano Clay-Biopolymer Composites for Drug Delivery

A magnetic antibody-conjugated nano-system for selective delivery of Ca(OH)2 and taxotere in ovarian cancer cells

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