Hair Loss and Plaquelike Skin Lesions

Cather, Jennifer Clay; Menter, M. Alan

doi:10.1080/08998280.2001.11927739

Cited by 2 publications

(1 citation statement)

References 31 publications

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“…However, non-steroidal anti-inflammatory drugs and antihistamines may be used for symptomatic relief [ 3 ]. Other nonspecific lesions associated with sarcoidosis include erythema multiforme, nummular eczema, and calcinosis cutis [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Sarcoidosis in Melanoma Patients: Case Report and Literature Review

Beutler¹,

Cohen²

2015

Cancers

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Sarcoidosis is a systemic inflammatory disease characterized by the development of noncaseating granulomas in multiple organ systems. Many hematologic malignancies and solid tumors, including melanoma, have been associated with sarcoidosis. We describe the clinical and pathologic findings of a 54-year-old man with melanoma-associated sarcoidosis. In addition, we not only review the literature describing characteristics of other melanoma patients with sarcoidosis, but also the features of melanoma patients with antineoplastic therapy-associated sarcoidosis. Sarcoidosis has been described in 80 melanoma patients; sufficient information for analysis was provided in 39 of these individuals. In 43.6% of individuals (17 out of 39), sarcoidosis was directly associated with melanoma; in 56.4% of oncologic patients (22 out of 39), sarcoidosis was induced by antineoplastic therapy that had been administered for the treatment of their metastatic melanoma. The discovery of melanoma preceded the development of sarcoidosis in 12 of the 17 (70.5%) individuals who did not receive systemic treatment. Pulmonary and/or cutaneous manifestations of sarcoidosis were common among both groups of patients. Most patients did not require treatment for sarcoidosis. Melanoma patients—either following antineoplastic therapy or without systemic treatment—may be at an increased risk to develop sarcoidosis. In antineoplastic therapy naive melanoma patients, a common etiologic factor—such as exposure to ultraviolet light—may play a role in their developing melanoma and sarcoidosis.

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Section: Discussionmentioning

confidence: 99%

Sarcoidosis in Melanoma Patients: Case Report and Literature Review

Beutler¹,

Cohen²

2015

Cancers

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Granulomatous disorders

Günaştı¹,

Aksungur²

2014

Clinics in Dermatology

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Almost all granulomatous skin disorders can cause red lesions on the face. Such disorders may include many bacterial, fungal, or parasitic infections, noninfectious inflammatory disorders, foreign body reactions, and even neoplasms. Clinically, they usually present with papules, plaques, nodules, and/or abscesses, which may ulcerate. It may be helpful in their differential diagnosis to define certain clinical patterns, such as multiple and discrete papules, necrotic or umbilicated papules or nodules, annular plaques, vegetative plaques or tumors, verrucous plaques or tumors, abscesses and/or sinuses, and lymphocutaneous pattern. Some disorders, such as sarcoidosis, can cause a wide variety of lesions. We accept that cutaneous leishmaniasis is also among such great imitators.

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Hair Loss and Plaquelike Skin Lesions

Cited by 2 publications

References 31 publications

Sarcoidosis in Melanoma Patients: Case Report and Literature Review

Sarcoidosis in Melanoma Patients: Case Report and Literature Review

Granulomatous disorders

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