Hailey‐Hailey disease on sun‐exposed areas

Heredity and Environment in Dermatological Diseases

“…Xeroderma Pigmentosa is associated with sensitivity to environmental sunlight (UVB) for most of its cutaneous effects; in Darier Disease both mechanical trauma and ultraviolet B exposure cause skin lesions; and in Hailey‐Hailey disease cutaneous infections, moisture, and friction cause skin lesions especially in interiginous areas. UVB has also been reported as an environmental factor worsening Hailey‐Hailey disease (12). Bloom syndrome patients show abnormal sensitivity to ultraviolet light; Dyskeratosis Congenita with ultraviolet sensitivity is associated with cutaneous malignancies; those of Celtic origin have increased sensitivity to ultraviolet light and increased numbers of skin cancers.…”

Hailey-Hailey disease on sun-exposed areas

“…He was a 63-year-old man who had multiple diseases (chronic obstructive pulmonary disease, paroxysmal atrial fibrillation, degenerative joint disease) and was on various medications (warfarin, aminophylline, N-acetylcystiene, ipratropium bromide, prednisolone). [8] However, the reported case is a young healthy lady and not on any medication. The exact role of sunlight in the provocation of FBCP in the reported case could not be established as the patient did not consent to the UV provocation test which could have helped in establishing its role in the pathogenesis of FBCP.…”